Archaeological contributions of skeletal lead analysis.

We developed a chemical method to quantitate lead in small skeletal specimens and used it to establish lead distribution and quantitation in modern skeletons for all age groups to standardize sampling sites. Application of the method to excavated ancient skeletal collections enabled prediction of socioeconomic status among Colonial Americans, as well as identification of lead poisoning in ancient Rome as related to lead production and in an 18th century Caribbean epidemic as related to distillation of rum. Depending upon the conditions of burial, bones may be contaminated by surrounding material.