Publications by authors named "George Pak-Man Cheng"
Article Synopsis
- LASIK surgery can cause temporary dry eye due to nerve damage, but this study investigates long-term ocular surface changes, blinking rates, and meibomian gland health in post-LASIK patients at least 48 months post-surgery.
- The study involved 48 post-LASIK patients and 48 matched healthy controls, assessing clinical findings and imaging related to eye health.
- Findings showed that post-LASIK patients had lower meibum quality, reduced tear production, and high chronic dry eye symptom prevalence, indicating the need for thorough evaluations and treatments for affected patients.
Purpose: This study aims to report correlations between thyroid-stimulating immunoglobulin (TSI) and both clinical and radiological parameters in recent-onset symptomatic thyroid eye disease (TED) patients.
Methods: A prospective cohort study of TED patients managed at the Chinese University of Hong Kong from January 2014 to May 2022. Serum TSI levels were determined with the functional assay.
Purpose: To investigate the differential expression of cytokines and growth factors in the cornea and aqueous humor after small incision lenticule extraction (SMILE) compared with femtosecond LASIK (FS-LASIK) using rabbit model.
Methods: Sixteen eyes of 16 rabbits in each group underwent SMILE or FS-LASIK with refractive correction of -6.00 DS/-1.
Purpose: To investigate real-time intraocular pressure (IOP) during small incision lenticule extraction (SMILE) in rabbit eyes for myopia correction.
Methods: During SMILE, real-time IOP was measured in the vitreous cavity of rabbit eyes with an optic fiber pressure sensor (OFPS). Two groups (n = 6 for each) underwent surgery, one group for a -2.
Objective: To investigate the biological effects of different intraocular lens (IOL) materials on the adhesion, migration, morphology, and epithelial-to-mesenchymal transition (EMT) of human lens HLEB3 cells.
Materials And Methods: Human HLEB3 cells were seeded onto IOLs composed of four different materials (polymethyl methacrylate (PMMA), silicone elastomer, hydrophilic acrylic, and hydrophobic acrylic). The levels of cellular adhesion, migration, morphology, and EMT were then quantified using a cell viability assay, scratch test, phase contrast microscopy, and immunofluorescence staining, respectively.
Objective: This paper aimed to review the current literature on the surface modification of intraocular lenses (IOLs).
Data Sources: All articles about surface modification of IOLs published up to 2015 were identified through a literature search on both PubMed and ScienceDirect.
Study Selection: The articles on the surface modification of IOLs were included, but those on design modification and surface coating were excluded.