Publications by authors named "George P Omondi"

Sleeping refuges-like other important, scarce and shareable resources-can serve as hotspots for animal interaction, shaping patterns of attraction and avoidance. Where sleeping sites are shared, individuals balance the opportunity for interaction with new social partners against their need for sleep. By expanding the network of connections within animal populations, such night-time social interactions may have important, yet largely unexplored, impacts on critical behavioural and ecological processes.

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  • Strengthening global health security requires effective vaccines and treatments against infectious diseases, with Toll-like receptor (TLR) agonists showing potential to enhance immune responses.
  • A systematic review of 653 studies identified 51 relevant studies, revealing that 82% focused on TLR agonists as vaccine adjuvants, while 18% explored them as therapeutic agents, with a strong emphasis on their effectiveness in stimulating immune responses in animals.
  • Although TLR agonists proved effective, only a few studies assessed their safety, highlighting the need for comprehensive safety evaluations before further clinical applications in animals.
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  • * A recent study investigated AMD use in pastoral communities in the Maasai Mara region, collecting data from 55 households and analyzing it with advanced statistical methods to reveal trends.
  • * Findings showed that AMD usage in cattle is linked to usage in sheep and goats, with less AMD use connected to vaccination against diseases and access to state veterinary services, highlighting the need for community-focused research to better understand these dynamics.
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Foot-and-mouth disease virus (FMDV) SAT2 sequences were acquired from Cape buffalo in Kenya in 2016, from either primary passage ( = 38) or plaque purification of dually SAT1/SAT2-infected samples ( = 61). All samples were derived from asymptomatic animals. These sequences contribute to our understanding of FMDV diversity in reservoirs and during subclinical FMDV infections.

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Nearly complete genomes of 49 novel foot-and-mouth disease virus (FMDV) SAT1 strains acquired from oropharyngeal fluid samples from asymptomatic African Cape buffalo in Kenya in 2016 were determined. Sequences were from primary passage or plaque-purified dually SAT1/SAT2-infected samples. These sequences are important for elucidation of the molecular epidemiology of persistent and subclinical FMDV infections.

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African buffalo are the natural reservoirs of the SAT serotypes of foot-and-mouth disease virus (FMDV) in sub-Saharan Africa. Most buffalo are exposed to multiple FMDV serotypes early in life, and a proportion of them become persistently infected carriers. Understanding the genetic diversity and evolution of FMDV in carrier animals is critical to elucidate how FMDV persists in buffalo populations.

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The COVID-19 pandemic has underscored the need to strengthen national surveillance systems to protect a globally connected world. In low-income and middle-income countries, zoonotic disease surveillance has advanced considerably in the past two decades. However, surveillance efforts often prioritise urban and adjacent rural communities.

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Crimean Congo Hemorrhagic Fever (CCHF) is an emerging tick-borne zoonotic viral disease with the potential of causing public health emergencies. However, less is known about the role of wildlife and livestock in spreading the virus. Therefore, we aimed to assess how the interactions between African buffalo () and cattle may influence the seroprevalence of CCHF across livestock-wildlife management systems in Kenya.

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  • Livestock movements play a crucial role in the spread of infectious diseases in pastoralist communities, but a lack of data limits effective disease control.
  • The study analyzed animal movement networks among villages in the Maasai Mara Ecosystem in Kenya, revealing that protected areas were key to maintaining village connectivity during the dry season.
  • Findings suggest that targeting specific, highly connected villages for interventions could be more effective in controlling disease transmission than random approaches, emphasizing the importance of network dynamics in disease management.
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Quantitative knowledge on the contribution of African buffalo to the epidemiology of foot-and-mouth disease virus (FMDV) in East Africa is lacking, and this information is essential for the design of control programs in the region. The objective of this study was to investigate the epidemiology of FMDV in buffalo, including the role of buffalo in the circulation of FMDV in livestock populations. We collected blood and oropharyngeal fluids from 92 wild buffalo and 98 sympatric cattle in central Kenya and sequenced the virus' VP1 coding region.

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Integrative management of wildlife and livestock requires a clear understanding of the diseases transmitted between the two populations. The tick-borne protozoan parasite Theileria parva causes two distinct diseases in cattle, East Coast fever and Corridor disease, following infection with parasites derived from cattle or buffalo, respectively. In this study, cattle were immunized with a live sporozoite vaccine containing three T.

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Obesity and ageing are emerging issues in the management of captive primates, including Chimpanzees, Pan troglodytes. Studies on humans show that obesity and old age can independently increase the risk of inflammatory-associated diseases indicated by elevated levels of pro-inflammatory cells and proteins in the blood of older or obese compared to levels in younger or non-obese individuals. In humans, sex can influence the outcomes of these risks.

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Parasitic infections transmitted between livestock and wildlife pose a significant risk to wildlife conservation efforts and constrain livestock productivity in tropical regions of the world. Gastrointestinal helminths are among the most ubiquitous parasites, and many parasites within this taxon can readily infect a wide range of host species. Factors shaping bidirectional transmission of parasites in wildlife-livestock systems are understudied.

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