Hashimoto's thyroiditis and papillary thyroid carcinoma. Are cytokeratin 19 and P63 proteins of any diagnostic value?

Background: The relation between Hashimoto's thyroiditis (HT) and papillary thyroid carcinoma (PTC) remains controversial. We aimed to study the coexistence of PTC and HT and the diagnostic utility of cytokeratin19 and P63 proteins expression in all positive for PTC cases of HT.

Subjects And Methods: We analyzed data from 343 patients who underwent fine needle aspiration cytology followed by thyroid surgery over a six years period.