Publications by authors named "George Ordiway"
The auditory brainstem response (ABR) is important for both clinical and basic auditory research. It is a non-invasive measure of hearing function with millisecond-level precision. The ABR can not only measure the synchrony, speed, and efficacy of auditory physiology but also detect different modalities of hearing pathology and hearing loss.
View Article and Find Full Text PDFThe chicken embryo is a widely accepted animal model to study the auditory brainstem, composed of highly specialized microcircuitry and neuronal topology differentially oriented along a tonotopic (i.e., frequency) axis.
View Article and Find Full Text PDFThe auditory brainstem response (ABR) is an invaluable assay in clinical audiology, non-human animals, and human research. Despite the widespread use of ABRs in measuring auditory neural synchrony and estimating hearing sensitivity in other vertebrate model systems, methods for recording ABRs in the chicken have not been reported in nearly four decades. Chickens provide a robust animal research model because their auditory system is near functional maturation during late embryonic and early hatchling stages.
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- The formation of complex tissues from simple epithelial sheets involves gene regulatory hierarchies that create distinct cell fates and rely on interactions between adjacent territories.
- Cells at territorial boundaries maintain separation not just through adhesion differences but also through mechanical asymmetries, particularly in cell properties like tension and structure.
- In the study of Drosophila leg development, it was found that the boundary between pretarsus and tarsus shows alignment and increased mechanical tension, highlighting the importance of Rho Kinase and Myosin II in maintaining this developmental boundary.