Publications by authors named "George O Silva"

The aim is to analyze the trend in breast cancer mortality rates and its correlation with the socioeconomic development status in Brazil. It involved an ecological time series study carried out in the 26 units of the federation, Federal District and regions of Brazil. Data sources included the Mortality Information System (number of deaths), the Brazilian Institute of Geography and Statistics (resident population) and the study of the Global Burden of Disease (Socio-demographic Index - SDI).

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Objective: to develop and validate the content of a serious game on the safe management of intravenous medications in pediatrics.

Method: methodological study for the development and content validation of an educational technology. The cases and challenges of the serious game were developed based on a literature review and validated by 11 nurses with training and experience in the area.

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Article Synopsis
  • The study analyzed cervical cancer mortality rates in Brazil from 2005 to 2019, finding a total of 105,472 deaths and an age standardized mortality rate (ASMR) of 10.18 deaths per 100,000 women.
  • The North region had the highest ASMR at 20.23, while the Southeast had the lowest at 7.83, with most regions showing decreasing trends except the North, which increased.
  • An association was identified between the Socio-demographic Index (SDI) and ASMR, indicating that higher SDI correlates with lower mortality rates for cervical cancer.
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Objectives: to categorize factual elements of ethical-disciplinary nursing lawsuits in the state of Goiás.

Methods: cross-sectional, retrospective study, based on secondary data obtained from ethical-disciplinary lawsuits filed at the Regional Nursing Council of Goiás (Coren-Goiás) between the years 2010 and 2019.

Results: the highest number of lawsuits filed was in 2013 and 2014, with a greater frequency in the state capital.

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Objective: To report the experience of the nursing supervised curricular internship in the program "O Brasil Conta Comigo" carried out in the Covid-19 pandemic.

Method: Experience report of activities developed in Primary Health Care in a municipality in the southern region of the state of Goiás during the Covid-19 pandemic, from April to November 2020.

Results: The inclusion in the government program allowed the strengthening of the student's active role in the teaching-learning process and teaching-service approximation, with the student as the point of connection, which resulted in the implementation of actions for the fight against the pandemic in the municipality, such as elaboration, implementation, and evaluation of the service flowchart for people with suspected Covid-19.

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Syntheses of the novel polymer-bound platinum-based chemotherapeutic agent poly(HPMA)-GGG-Ama=Pt=(1R,2R)-DACH, AP5346, and its precursors are reported. The method utilized in preclinical development of AP5346 is described herein. Additionally, an improved synthesis, which has shown that ion exchange resins can be removed, significantly less platinum can be used when the reaction mixture is pH-stated, and the synthesis can be performed at a higher concentration, is reported.

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