Fragility hip fractures have become a worldwide epidemic with serious socioeconomic implications. The projected number of hip fractures by 2050 is estimated to reach 4.5 million cases.
View Article and Find Full Text PDFBackground: Microgravity (μG) negatively influences bone metabolism by affecting normal osteoblast and osteoclast function. μG effects on bone metabolism has been an extensive field of study in recent years, due to the challenges presented by space flight.
Methods: We systematically reviewed research data from genomic studies performed in real or simulat-ed μG, on osteoblast and osteoclast cells.