Publications by authors named "George Malindzak"

Background: Asthma-associated morbidity is rising, especially in inner city children.

Objective: We evaluated the allergen sensitivities, allergen exposures, and associated morbidity for participants in the Inner City Asthma Study. We also determined geographic variations of indoor allergen levels.

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Article Synopsis
  • - This study focused on children aged 5 to 11 with asthma living in urban areas, who often face high exposure to indoor allergens and tobacco smoke at home.
  • - A year-long environmental intervention was tested to reduce these triggers and involved education and remediation strategies tailored to each child’s specific allergens and risks.
  • - Results showed that children in the intervention group experienced fewer asthma symptoms and lower allergen levels at home, leading to significant decreases in asthma-related complications compared to a control group.
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Most published environmental remediation interventions have been directed at single allergens and have employed demanding strategies; few have been performed in the homes of inner-city children disproportionately burdened by asthma. Our objective was a) to describe the allergen sensitivities, environmental tobacco smoke (ETS) exposure, and home environmental characteristics of a national sample of inner-city children with moderate to severe asthma and b) to develop and implement a multifaceted, home-based comprehensive intervention to reduce home allergens and ETS, tailored to the specific sensitization and exposure profiles of those children. Allergen skin testing and a home evaluation were performed to determine the presence of ETS and factors known to be associated with increased indoor allergen levels.

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