The American chestnut, once dominant in the Appalachian Forest, was nearly wiped out by an invasive fungus called chestnut blight, while the Chinese chestnut is resistant to this disease.
Efforts to restore the American chestnut’s resistance involve backcross breeding with the Chinese chestnut and advancements in genetic engineering.
Recent research mapped the genomes of both chestnut species, revealing differences in their ribosomal DNA distribution and chromatin organization, highlighting specific sites of rDNA that could be important for understanding their genetics.