Skin Toxicity: Clinical Summary of the ONS Guidelines™ for Cancer Treatment-Related Skin Toxicity.

Cancer treatment-related skin toxicities are a frequent and distressing side effect of antineoplastic therapies, especially chemotherapy and targeted therapies. Skin toxicities associated with these therapies can include rashes, hand-foot skin reaction, hand-foot syndrome, and hair loss. These symptoms cause not only physical pain and discomfort but also psychological distress, and they can become a stigma of the patient's cancer diagnosis.

ONS Guidelines™ for Cancer Treatment-Related Skin Toxicity.

Background: Management of cancer treatment-related skin toxicities can minimize treatment disruptions and improve patient well-being.

Objectives: This guideline aims to support patients and clinicians in decisions regarding management of cancer treatment-related skin toxicities.

Methods: A panel developed a guideline for management of cancer treatment-related skin toxicities using GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) for certainty of evidence and the National Academies of Sciences, Engineering, and Medicine criteria for trustworthy guidelines.