Radical nephrectomy with transperitoneal subcostal incision for large and locally advanced tumors of the right kidney.

Background: Several surgical approaches have been used for radical nephrectomy for large and locally advanced tumors of the right kidney.

Aim: To present our experience with radical nephrectomy using a right subcostal incision with a transperitoneal approach in patients with very large tumors of the right kidney.

Patients And Methods: Between 2003 and 2010, 34 patients with very large tumors of the right kidney were submitted to surgery.

Early removal of nasogastric tube is beneficial for patients undergoing radical cystectomy with urinary diversion.

Purpose: Examine the beneficial effect of early nasogastric tube (NGT) removal in patients undergoing radical cystectomy with urinary diversion.

Patients And Methods: 43 consecutive patients underwent radical cystectomy with urinary diversion and were randomized into 2 groups. In the intervention group (n = 22), the NGT was removed 12 hours after the operation.

The effect of alpha-blocker treatment on bladder hypoxia inducible factor-1 alpha regulation during lower urinary tract obstruction.

Aims: To determine whether alpha1-blocker treatment, in chronic bladder outlet obstruction (BOO), influences bladder tissue ischemia.

Materials And Methods: This prospective study included 60 patients with BOO, of which 40 were under alpha1-blocker medication and 20 without treatment. Patients underwent transurethral resection of the prostate (TURP) or suprapubic prostatectomy (SPP).

Immunohistochemical estimation of hypoxia in human obstructed bladder and correlation with clinical variables.

Objective: To investigate the tissue distribution of ischaemia in human detrusor in patients with bladder outlet obstruction (BOO) and to correlate the results with clinical variables, as clinical BOO is a common problem in ageing men and ischaemia might be important in detrusor dysfunction.

Patients And Methods: From September 2004 to October 2006, 70 patients were recruited, comprising 60 scheduled for surgery to treat benign prostatic hyperplasia (the study group) and 10 as controls. Detrusor tissue was retrieved and stained for hypoxia-inducible factor (HIF)-1alpha, a cellular marker of hypoxia.