Intravenous vs Intra-Articular Tranexamic Acid in Total Knee Arthroplasty: A Randomized, Double-Blind Trial.

Background: Tranexamic acid (TXA) is commonly used in primary total knee arthroplasty (TKA); however, the most appropriate route of administration is still debated. This study was conducted to compare the 2 most commonly used routes of TXA administration, intravenous (IV) and intra-articular (IA).

Methods: This study was conducted as a double-blind, randomized, noninferiority trial and included patients undergoing primary unilateral TKA.

Osteolysis in third-generation alumina ceramic-on-ceramic hip bearings with severe impingement and titanium metallosis.

The most common cause of long-term failure of total hip arthroplasty is osteolysis and aseptic loosening secondary to wear debris. Combinations of hard materials such as ceramic-on-ceramic generate smaller volumes of particulate wear debris than traditional combinations such as metal-on-polyethylene. We describe 2 cases where osteolysis arose in hips with third-generation alumina ceramic-on-ceramic couplings.

Extramedullary femoral alignment instrumentation reduces blood loss after uncemented total knee arthroplasty.

The influence of different femoral alignment systems on blood loss and the need for blood transfusion after total knee arthroplasty (TKA) was studied. The blood loss was retrospectively recorded in two similar groups of consecutive patients. The first group consisted of 46 patients in whom TKA was performed using the intramedullary femoral alignment system and the second group consisted of 45 patients in whom the procedure was performed with the extramedullary system.

An incidental finding of chondroid lipoma at total hip arthroplasty.

Chondroid lipoma is a rare benign lipomatous soft tissue tumor which presents as a painless lump. This case report presents the incidental finding of such a tumor at total hip replacement and briefly reviews the literature regarding the histopathological features of this recently described neoplasm.