An Organic Mineral Adhesive Bone Graft: A Preclinical Study.

The development of a successful bone grafting technology with cohesive and adhesive properties has been an elusive goal for dental and orthopedic researchers. Tetracalcium phosphate combined with phosphoserine (TTCP-PS) is a synthetic, injectable, cohesive, self-setting, mineral-organic wet-field adhesive. The objective of this study was to evaluate four formulations of TTCP-PS in comparison to the conventional grafting materials, Bioglass and deproteinized cancellous bovine bone with a bioresorbable collagen membrane in standardized defects created in the angle of the rat mandible.

Trends Favoring an Anatomical Approach to Radiofrequency Catheter Ablation of Idiopathic Ventricular Arrhythmias Originating From the Left Ventricular Summit.

Background: Epicardial radiofrequency catheter ablation (RFCA) of idiopathic ventricular arrhythmias (VAs) originating from the left ventricular summit (LVS) is challenging because of the anatomic barriers. On the other hand, RFCA at the endocardial sites near the earliest epicardial activation site of LVS-VAs (anatomic approach) has proven successful. The evolving trends in the approaches and outcomes of RFCA of LVS-VAs at a single center were evaluated.

Tuning the Functionalization of Graphite for Hydrovoltaic Power Generation.

The recent discovery of hydrovoltaic devices for power generation has led to a rapid growth into new materials for harvesting energy specifically for this research field. Of the materials investigated, carbon materials have dominated, and graphene oxide (GO) has emerged as the leader. While graphite is conductive, it does not have functional groups to strongly interact with water, and highly functionalized GO forms strong interaction with water to generate necessary surface charges but does not typically have high conductivity.

Twelve-month evaluation of a novel mineral-organic adhesive material used to stabilize dental implants placed in oversized osteotomies in vivo in an animal model.

Objectives: The aim of this study is to evaluate long-term in vivo stability of dental implants stabilized at time of placement in oversized osteotomies with a novel, self-setting, mineral-organic bone adhesive.

Materials/methods: Canine (26) mandibular teeth were removed, and three oversized osteotomies prepared bilaterally. Implants were placed with either adhesive, particulate xenograft, or with blood clot filling the implant/osteotomy gaps.

Immediate Dental Implant Stabilization in a Canine Model Using a Novel Mineral-Organic Adhesive: 4-Month Results.

Purpose: This study evaluated a novel injectable, self-setting, osteoconductive, resorbable adhesive that provides immediate implant stabilization.

Materials And Methods: Twenty-six large canines had the mandibular second through fourth premolars and the first molar removed bilaterally. After 3 months, oversized osteotomies were prepared with only the apical 2 mm of the implant engaging native bone.

Typical atrial flutter mimicking a pacemaker-mediated tachycardia.

A 64-year-old man with a history of congestive heart failure secondary to nonischemic cardiomyopathy, mitral and aortic valve replacements, and biventricular cardioverter-defibrillator placement, developed a tachycardia. The tachycardia exhibited a biventricular paced rhythm with a short R-P interval and concentric atrial activation sequence within the coronary sinus, suggesting that the tachycardia might be a pacemaker-mediated tachycardia (PMT). However, the tachycardia was diagnosed as counterclockwise cavotricuspid isthmus (CTI)-dependent atrial flutter (AFL), and linear ablation of the CTI eliminated the tachycardia.

Focal ventricular arrhythmias originating from the left ventricle adjacent to the membranous septum.

Aims: We report the features of focal ventricular arrhythmias (VAs) arising from the left ventricle (LV) adjacent to the membranous septum.

Methods And Results: We studied eight patients (five men, 65 ± 10 years) with (n = 2) or without structural heart disease (n = 6) who had ventricular tachycardia (n = 4) or premature ventricular contractions (n = 4) originating from the LV septum underneath the aorta. Ventricular arrhythmias exhibited a focal activation pattern, left (n = 4) or right bundle branch block (n = 4), respectively, left superior (n = 4) or inferior axis QRS morphology (n = 4), negative QRS polarity in lead III and early or no precordial transition in all.

QRS alternans during idiopathic ventricular tachycardia originating from the right coronary cusp of the aorta.

A 77-year-old man underwent electrophysiological testing for idiopathic ventricular tachycardia (VT) with QRS alternans exhibiting a left bundle branch block and left inferior axis QRS morphology. Successful radiofrequency catheter ablation was achieved at the site of the earliest ventricular activation in the right coronary cusp. Pacing at this site reproduced an excellent pace map with QRS alternans.

Electroanatomic mapping in the catheter ablation of premature atrial contractions with a non-pulmonary vein origin.

Symptomatic premature atrial contractions (PACs) may be a target for catheter ablation. However, mapping of PACs with an atrial origin may not be easy because of erratic incidence and different sites of origin. Although the technique and efficacy of electroanatomic mapping has been established in stable arrhythmias, electroanatomic mapping of PACs in intermittent arrhythmias has not yet been reported.

Successful catheter ablation of premature ventricular contractions originating from the tricuspid annulus using a Halo-type catheter.

A 31-year-old woman with idiopathic premature ventricular contractions originating from the tricuspid annulus (TA) underwent electrophysiological testing. Activation mapping with a 20-pole bipolar Halo-type catheter positioned along the TA revealed the earliest ventricular activation at a site between 7 and 8 o'clock along the TA. A reversal in the polarity of the local ventricular electrograms was observed between the two neighbouring electrode pairs of the TA catheter.

Successful catheter ablation of atrial fibrillation in a patient with dextrocardia.

A 49-year-old woman with dextrocardia and situs inversus underwent catheter ablation of paroxysmal atrial fibrillation. A contrast injection into the left atrium revealed that the left atrial appendage (LAA) was adjacent to the right-sided (anatomic left) superior pulmonary vein (PV). After successful isolation of that PV, LAA potentials were recorded from several electrode pairs of a circular PV mapping catheter.

Duplicated coronary sinus with a connecting branch.

A 48-year-old woman with class III heart failure and left bundle branch block underwent an implantation for cardiac resynchronization therapy. Right anterior oblique (RAO) view coronary sinus (CS) venography suggested the antero- and postero-lateral branches appeared to arise from the same vessel of a duplicated CS, but the antero-lateral branch arising from a different vessel was visualized via a connecting branch by the contrast injected into the vessel with the postero-lateral branch, and the distal parts of the two vessels were superimposed in the RAO view. This unusual anomaly may have the potential risk for complications such as perforations.