Publications by authors named "George Huo"
Article Synopsis
- A high-quality genome of rosemary (Salvia rosmarinus) was generated, revealing 46,121 protein-coding genes and a significant genome duplication around 28.3 million years ago, enhancing understanding of its evolution and environmental adaptation.
- Comparative analysis showed rosemary's close genetic relationship with Salvia splendens and Salvia miltiorrhiza, with 1,918 gene families expanded, 35 involved in producing antioxidant components important for environmental resilience.
- Multi-omics analysis indicated that certain antioxidant biosynthesis genes were up-regulated during abiotic stress, demonstrating how rosemary adapts to harsh conditions by stabilizing ROS levels and supporting cell functionality through integrated metabolic processes.
HOLLYWOOD: a comparative relational database of alternative splicing.
Nucleic Acids Res
January 2006
RNA splicing is an essential step in gene expression, and is often variable, giving rise to multiple alternatively spliced mRNA and protein isoforms from a single gene locus. The design of effective databases to support experimental and computational investigations of alternative splicing (AS) is a significant challenge. In an effort to integrate accurate exon and splice site annotation with current knowledge about splicing regulatory elements and predicted AS events, and to link information about the splicing of orthologous genes in different species, we have developed the Hollywood system.
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