Publications by authors named "George Hone"
Open Forum Infect Dis
September 2020
Article Synopsis
- The study evaluates a new immunofluorescent antibody assay for detecting SARS-CoV-2-specific antibodies (IgG, IgA, IgM) compared to standard nucleic acid tests (NAT) in diagnosing COVID-19.
- A total of 2,753 individuals were analyzed, revealing high sensitivity (91.3%) and specificity (98.9%) for antibody detection after symptoms appear, with a significant window period of about 10.2 days for antibody development.
- The findings suggest incorporating serological tests into COVID-19 diagnostic protocols to identify cases missed by NAT and highlight the strong antibody responses most individuals develop post-infection, though uncertainties about their longevity remain.
