Publications by authors named "George Hixson"

Article Synopsis
  • The study investigates the effectiveness of hydrogel spacers (HS) in reducing radiation exposure to the rectum for prostate cancer patients receiving combination-brachytherapy (CBT).
  • A comparison between 30 patients with HS and 30 without HS showed that those with HS had significantly lower radiation doses to the rectum, which suggests that HS use enhances dosimetric outcomes.
  • The findings suggest that thicker HS (≥1 cm) are more effective in minimizing rectal radiation exposure, highlighting the importance of proper placement for achieving better outcomes in radiation therapy.
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Post-implant dosimetric analysis for permanent implant of the prostate benefits from the use of a computed tomography (CT) dataset for optimal identification of the radioactive source (seed) positions and a magnetic resonance (MR) dataset for optimal description of the target and normal tissue volumes. The CT/MR registration process should be fast and sufficiently accurate to yield a reliable dosimetric analysis. Since critical normal tissues typically reside in dose gradient regions, small shifts in the dose distribution could impact the prediction of complication or complication severity.

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Purpose: To determine the feasibility of registration of MRI and CT datasets post permanent prostate implant by the use of mutual information.

Methods And Materials: Five patients who underwent permanent (125)I implant for prostate carcinoma were studied. Two weeks postimplant an axial CT, T2-weighted-axial, sagittal and coronal MRI, and T1-fat-saturation MRI scans were obtained.

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