Publications by authors named "George F Gade"
Objective: Omentum transposition surgery (OT) applied to various neurodegenerative disorders has produced clinically significant improvement, which may be due to omentally-derived factors. To evaluate the clinical effect of left hemisphere OT in a primary progressive aphasia (PPA) patient, 3 year follow-up data were analysed.
Methods: Left hemisphere OT was performed on a 68-year-old male with PPA, characterized by moderate dementia and severe expressive aphasia with relatively preserved comprehension, object recognition and visual-spatial abilities.
Article Synopsis
- The study aimed to assess the impact of omentum transposition surgery (OT) on patients with Alzheimer's disease (AD) using a repeated-measures design involving six biopsy-confirmed cases.
- Results showed that OT led to significant improvements in cognitive and behavioral measures, with reductions in dementia severity scores and notable long-term benefits for patients with behavioral issues.
- OT demonstrated a 34-fold greater likelihood of achieving meaningful clinical improvement compared to standard cholinesterase inhibitor therapy, suggesting a need for further research into how the omentum may exert its therapeutic effects.