Vulvovaginal Involvement in Pediatric Stevens-Johnson Syndrome: A Case Series.

Background: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening spectra of mucocutaneous delayed hypersensitivity reactions. Prodromal viral-like symptoms are followed by a characteristic diffuse rash caused by keratinocyte apoptosis and epidermal detachment.

Cases: Three adolescents were admitted with SJS/TEN and vulvovaginal involvement following initiation of lamictal, bactrim, and phenobarbital.

Epicutaneous Staphylococcus aureus induces IL-36 to enhance IgE production and ensuing allergic disease.

IgE induced by type 2 immune responses in atopic dermatitis is implicated in the progression of atopic dermatitis to other allergic diseases, including food allergies, allergic rhinitis, and asthma. However, the keratinocyte-derived signals that promote IgE and ensuing allergic diseases remain unclear. Herein, in a mouse model of atopic dermatitis-like skin inflammation induced by epicutaneous Staphylococcus aureus exposure, keratinocyte release of IL‑36α along with IL-4 triggered B cell IgE class-switching, plasma cell differentiation, and increased serum IgE levels-all of which were abrogated in IL-36R-deficient mice or anti-IL‑36R-blocking antibody-treated mice.

The effect of smoking and age on the response to first-line therapy of hidradenitis suppurativa: An institutional retrospective cohort study.

Background: Treatment for hidradenitis suppurativa is often empiric and inadequate, and determining which patients will respond is difficult.

Objective: We sought to determine which patient factors are associated with a positive response to first-line medical therapy.

Methods: A single-center retrospective cohort study of all patients with hidradenitis suppurativa seen between January 1, 1992, and October 1, 2014, was conducted.

Blockade of ENaCs by amiloride induces c-Fos activation of the area postrema.

Epithelial sodium channels (ENaCs) are strongly expressed in the circumventricular organs (CVOs), and these structures may play an important role in sensing plasma sodium levels. Here, the potent ENaC blocker amiloride was injected intraperitoneally in rats and 2h later, the c-Fos activation pattern in the CVOs was studied. Amiloride elicited dose-related activation in the area postrema (AP) but only ~10% of the rats showed c-Fos activity in the organum vasculosum of the lamina terminalis (OVLT) and subfornical organ (SFO).

Hiding the word: examining the relationship between a new measure of religiosity and sexual behavior.

The relationship between religiosity and sexual behavior has been previously investigated, but researchers have not examined the relationship between the intellectual dimension of religiosity and sexual behavior. In this study, we developed an intellectual measure of religiosity, Hiding the Word (HTW), and examined whether it accounted for variation in the sexual behavior of college students, beyond that for which age and a generic measure of religiosity could account. Results showed, after accounting for age and generic religiosity, HTW made a significant contribution to distinguishing between students who had, and those who had not, engaged in various sexual behaviors.

Lessons from the trenches: meeting evaluation challenges in school health education.

Background: Those involved in school health education programs generally believe that health-education programs can play an important role in helping young people make positive health decisions. Thus, it is to document the effects of such programs through rigorous evaluations published in peer-reviewed journals.

Methods: This paper helps the reader understand the context of school health program evaluation, examines several problems and challenges, shows how problems can often be fixed, or prevented, and demonstrates ways in which challenges can be met.

An evaluation of an abstinence-only sex education curriculum: an 18-month follow-up.

The article examines the results from an 18-month follow-up evaluation of an abstinence education curriculum series. Participants were students from 15 school districts recruited to participate in the project. The intervention was the Sex Can Wait curriculum series, consisting of upper elementary, middle school, and high school components.

A survey of patients with inflatable penile prostheses for satisfaction.

Purpose: We assessed patient satisfaction with 3 types of penile prostheses, namely the AMS 700 Series(R), Mentor Alpha 1(R) and Mentor Alpha NB(R).

Materials And Methods: The subjects consisted of 330 patients selected by stratified, systematic random sampling from among 1,298 subjects undergoing virgin 3-piece inflatable penile implant surgeries performed by the same surgical team at 1 hospital between January 1992 and December 1998. Data were collected by computer assisted telephone interviewing with a survey developed by the authors.

Examining external and internal poverty as antecedents of teen pregnancy.

Objectives: To identify antecedents of teen pregnancy.

Methods: Data from the National Education Longitudinal Study were analyzed. This data set allowed us to identify eighth-grade antecedents of teen pregnancy/childbearing.

The impact of telemedicine on patients' cost savings: some preliminary findings.

This study evaluated patients' cost savings in a telehealth project at the University of Arkansas for Medical Sciences' (UAMS) during 1998-2002. Differences in patients' cost savings from telemedicine were assessed by gender, age, ethnicity, education, occupation, annual household income, health insurance status, and household and community size. Variables examined for patients' cost savings included travel distance for medical care, missed days at work, and family expenses.

Bone mineral density levels of college-aged women in northwest Arkansas.

Osteoporosis has affected more than 20 million American, women, completely altering their way of life. Osteoporosis is highly preventable if steps are taken to build healthy bone; however, many college students do not have lifestyle habits that have a positive effect on their bones. For this study, a questionnaire was used to investigate childhood dairy consumption, high school sport participation, dieting behaviors, eating behaviors and bone mineral density levels of college women at the University of Arkansas in Fayetteville.

Participant satisfaction in an adult telehealth education program using interactive compressed video delivery methods in rural Arkansas.

Context: Rural Americans have less access than their urban counterparts to health promotion information.

Purpose: To assess differences in program satisfaction associated with age, gender, ethnicity, community size, and education among participants in an Arkansas adult telehealth education program that utilized interactive video technology.

Methods: A program evaluation instrument was administered to a convenience sample of 2567 people who participated in the program from 1996 through 1999.

An evaluation of an abstinence education curriculum series: sex can wait.

Objective: To examine the effects of an abstinence education curriculum series on student outcomes.

Methods: The series was taught at upper elementary, junior high, and high school levels. A questionnaire was administered to all intervention and comparison students before and after implementation of the curriculum.

Participant satisfaction with a school telehealth education program using interactive compressed video delivery methods in rural Arkansas.

Socioeconomic and demographic factors can affect the impact of telehealth education programs that use interactive compressed video technology. This study assessed program satisfaction among participants in the University of Arkansas for Medical Sciences' School Telehealth Education Program delivered by interactive compressed video. Variables in the one-group posttest study were age, gender, ethnicity, education, community size, and program topics for years 1997-1999.