Economical hybrid novelty detection leveraging global aleatoric semantic uncertainty for enhanced MRI-based ACL tear diagnosis.

This study presents an innovative hybrid deep learning (DL) framework that reformulates the sagittal MRI-based anterior cruciate ligament (ACL) tear classification task as a novelty detection problem to tackle class imbalance. We introduce a highly discriminative novelty score, which leverages the aleatoric semantic uncertainty as this is modeled in the class scores outputted by the YOLOv5-nano object detection (OD) model. To account for tissue continuity, we propose using the global scores (probability vector) when the model is applied to the entire sagittal sequence.

Postoperative Infection after Anterior Cruciate Ligament Reconstruction: Prevention and Management.

Infection following anterior cruciate ligament (ACL) reconstruction can be one of the most debilitating complications following ACL reconstruction. Its reported incidence is around 1%. Utilization of vancomycin for presoaking the graft is considered an established method for infection prevention.

The effect of zoledronic acid and high-dose vitamin D on function after hip fractures. A prospective cohort study.

Purpose: Hip fractures are associated with functional decline and increased mortality. The aim of this study was to investigate the effect of zoledronic acid and high-dose vitamin D on function and mortality after hip fractures.

Patients And Methods: Forty-five patients received zoledronic acid and high dose of vitamin D during hospitalization after fracture management.

Soaking of autografts with vancomycin is highly effective on preventing postoperative septic arthritis in patients undergoing ACL reconstruction with hamstrings autografts.

Purpose: To evaluate the impact of local soaking of the autografts with vancomycin during anterior cruciate ligament (ACL) reconstruction on postoperative infection rates.

Methods: Between 2003 and 2014 (first study period), 1,242 patients underwent ACL reconstruction using autografts, without soaking them in vancomycin solution, while between 2014 and 2019 (second study period) all ACL autografts in 593 patients were soaked in a 5-mg/ml vancomycin solution, in a territory University Hospital. The same standard treatment of perioperative IV antibiotics was applied in both groups.