Publications by authors named "Georg J Loss"
Article Synopsis
- This study examines the link between cord blood cytokine production and respiratory tract infections in infants during their first year, focusing on immune regulation factors.
- Researchers analyzed data from a birth cohort of 550 children from rural areas in Europe, assessing cytokine levels using blood samples and tracking infection symptoms through weekly diaries.
- Results indicate that higher levels of certain cytokines (IL-5 and IFN-γ) in cord blood are associated with fewer reports of middle ear infections, suggesting that stronger immune responses at birth may help protect against these types of infections.
The Early Development of Wheeze. Environmental Determinants and Genetic Susceptibility at 17q21.
Am J Respir Crit Care Med
April 2016
Rationale: Growing up on a farm protects from childhood asthma and early wheeze. Virus-triggered wheeze in infancy predicts asthma in individuals with a genetic asthma risk associated with chromosome 17q21.
Objectives: To test environmental determinants of infections and wheeze in the first year of life, potential modifications of these associations by 17q21, and the implications for different trajectories of wheeze.