Publications by authors named "Geon Hyung Jeon"
Article Synopsis
- * During this inactive phase, the blood-testis barrier (BTB) loses its integrity, causing developing germ cells to either be engulfed by Sertoli cells or slough off, leading to the absence of sperm in most epididymis regions.
- * Key genes responsible for tight junctions in the BTB (like claudin-11 and occludin) are present in active testes but not in inactive ones, indicating that structural disorganization of the BTB is linked to testicular regression and the removal of germ
Article Synopsis
- Melatonin has been shown to cause testicular regression in seasonal breeding animals, particularly in male Syrian hamsters when injected in the afternoon.
- A study examined the effects of different dosages of melatonin given daily via gavage on hamsters kept in long and short photoperiods over 8 weeks.
- Results indicated that higher doses of melatonin led to significant testicular shrinkage compared to controls, with low doses having no adverse effect, similar to the large testes seen in the long photoperiod control group.
