Publications by authors named "Geoffroy Vanbiervliet"

Background: Achieving competence in endoscopic retrograde cholangiopancreatography (ERCP) requires extensive training. Recognizing the potential of simulator-based education for safe and effective skill development, we aimed to assess whether initial training with the Boškoski-Costamagna ERCP Trainer (BCT) is beneficial compared with conventional training alone (i.e.

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Digestive endoscopy is a highly dynamic medical discipline, with the recent adoption of new endoscopic procedures. However, comprehensive guidelines on the role of antibiotic prophylaxis in these new procedures have been lacking for many years. The Guidelines Commission of the French Society of Digestive Endoscopy (SFED) convened in 2023 to establish guidelines on antibiotic prophylaxis in digestive endoscopy for all digestive endoscopic procedures, based on literature data up to September 1, 2023.

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Objectives: Endoscopic ultrasound-guided gastrojejunostomy (EUS-GJ) is an alternative to duodenal stenting and surgical GJ (SGGJ) in malignant gastric outlet obstruction (MGOO). European Society of Gastrointestinal Endoscopy guidelines restricted EUS-GJ for MGOO only, because of misdeployment. The aim was to evaluate its outcomes focusing on benign indications.

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  • A multicenter study assessed the feasibility and safety of EUS-guided fiducial marker placement in patients with esophageal or rectal cancer referred for radiation therapy, focusing on success rates and outcomes.
  • The study involved 33 patients, achieving a 93.9% success rate in marker placement, with an average procedure time of 12.5 minutes and no reported adverse events.
  • Results showed that all fiducial markers remained visible throughout radiation therapy, emphasizing the approach's safety and effectiveness for these cancer types.
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Introduction: The adoption of colorectal endoscopic submucosal dissection (ESD) is still limited in the West. A recent randomized trial showed that ESD is more effective and only slightly riskier than piecemeal endoscopic mucosal resection; reproducibility outside expert centers was questioned. We evaluated the results according to the annual case volume in a multicentric prospective cohort.

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Purpose: Gastric outlet obstruction (GOO) is mainly due to advanced malignant disease. GOO can be treated by surgical gastroenterostomy (SGE), endoscopic enteral stenting (EES), or endoscopic ultrasound-guided gastroenterostomy (EUS-GE) to improve the quality of life.

Methods: Between 2009 and 2022, patients undergoing SGE or EUS-GE for GOO were included at three centers.

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Background:  Computer-aided detection (CADe) has been developed to improve detection during colonoscopy. After initial reports of high efficacy, there has been an increasing recognition of variability in the effectiveness of CADe systems. The aim of this study was to evaluate a CADe system in a varied colonoscopy population.

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  • Missed lesions during colonoscopy can lead to post-procedure colorectal cancer, prompting the development of contrast-enhanced technologies like linked color imaging (LCI) for better polyp detection.
  • A national, randomized trial compared polyp detection rates between standard white-light imaging (WLI) and LCI in the right colon, involving 764 patients across 10 endoscopy units.
  • Results showed no significant difference in the proximal adenoma miss rate or miss rates for other types of lesions between the WLI-first and LCI-first groups, challenging the idea that LCI improves detection in routine colonoscopy.
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Optical diagnosis poses challenges to implementation of "resect and discard" strategies. This study aimed to assess the feasibility and performance of a new commercially available system for colorectal polyps. Nine expert endoscopists in three centers performed colonoscopies using artificial intelligence-equipped colonoscopes (CAD EYE, Fujifilm).

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The costs of reusable endoscope reprocessing have been evaluated, yet external validity of the findings remains challenging. The aim of this study was to assess the costs of purchase, maintenance, microbiological control, and reprocessing of a reusable duodenoscope per endoscopic retrograde cholangiopancreatography (ERCP) in France. Study findings exclude the costs of infection, downtime due to breakdown, reprocessing single-use material disposal, and device disposal, all of which should also be considered.

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INTRODUCTION : Residual colorectal neoplasia (RCN) after previous endoscopic mucosal resection is a frequent challenge. Different management techniques are feasible including endoscopic full-thickness resection using the full-thickness resection device (FTRD) system and endoscopic submucosal dissection (ESD). We aimed to compare the efficacy and safety of these two techniques for the treatment of such lesions.

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  • - The study investigated the safety and effectiveness of endoscopic resection for early esophageal tumors in patients with liver cirrhosis or portal hypertension, given their shared risk factors like alcohol use and obesity.
  • - It analyzed data from 112 patients who underwent this procedure between 2005 and 2021, finding that a majority had liver cirrhosis, and various methods were employed to reduce bleeding risks during the surgery.
  • - Results showed high rates of complete and curative resection but also identified some adverse events, such as delayed bleeding and infections; the findings suggest that expert centers should perform these procedures following established guidelines to ensure patient safety and treatment effectiveness.
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  • A study aimed to understand the prevalence of small intestinal bacterial overgrowth (SIBO) in patients with irritable bowel syndrome (IBS) and its correlation with the levels of hydrogen and methane measured during breath tests.
  • Among 247 IBS patients, 36.4% were found to have SIBO, with those predominantly constipated showing higher methane levels and those with diarrhea showing higher hydrogen levels.
  • The research concluded that while SIBO is common in IBS, it doesn’t correlate with the severity of IBS, suggesting that personal pain sensitivity may play a bigger role in IBS symptoms.
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  • EUS-guided radiofrequency ablation (EUS-RFA) is being evaluated as a safe and effective treatment for solid and cystic pancreatic tumors in a large study with 100 patients in France.
  • The study found that while there were no deaths from the procedure, 22 adverse events occurred, primarily linked to how close the tumors were to the main pancreatic duct.
  • Overall, the treatment showed promising results with 60.2% of patients achieving complete tumor response, particularly effective for smaller neuroendocrine neoplasms.
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BACKGROUND : The diagnosis of cholangiocarcinoma in patients with a biliary stricture without mass syndrome can be obtained by biliary brushing with a sensitivity of ~50 %. We performed a multicenter randomized crossover trial comparing the aggressive Infinity brush with the standard RX Cytology Brush. The aims were to compare sensitivity for cholangiocarcinoma diagnosis and cellularity obtained.

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Background: Gastric per oral endoscopic esophageal myotomy (G-POEM) is a promising procedure to treat refractory gastroparesis. The safety profile of G-POEM is an important topic because gastroparesis is a functional pathology, with a procedure whose effectiveness is between 50 and 65% depending on the studies.

Objectives: We present this retrospective multicenter study, with the aim of establishing a safety profile, focusing on serious adverse events (AEs).

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Background And Aims: No recommendation regarding antibiotic prophylaxis and preparation modalities are available for patients with esophageal motor disorders who benefit from Per-Oral Endoscopic Myotomy (POEM). The aim of our study was to evaluate their impact on the POEM's safety.

Patients And Methods: This study was a comparative and multicentric retrospective analysis of a database prospectively collected.

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Objective: To provide guidelines for the management of the intensive care patient with severe acute pancreatitis.

Design: A consensus committee of 22 experts was convened. A formal conflict-of-interest (COI) policy was developed at the beginning of the process and enforced throughout.

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Background: Little is known about small bowel capsule endoscopy (SBCE) outcomes in patients with surgically altered anatomy.

Aims: To assess the feasibility and diagnostic yield of orally ingested SBCE to investigate obscure gastrointestinal bleeding (OGIB) in patients with surgically altered gastric anatomy, compared to native gastric anatomy.

Methods: 207 patients with OGIB were selected from an open, multicenter, retrospective cohort (SAGA study) and match-paired according to age, gender and bleeding type (overt/occult) to 207 control patients from a randomized controlled trial (PREPINTEST).

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  • The study evaluated the long-term effectiveness of endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) for treating pancreatic neuroendocrine tumors (NETs) and certain pancreatic cystic neoplasms (PCNs) over a follow-up period of at least 3 years.
  • Out of the participants, a high percentage (85.7%) of NETs showed complete tumor disappearance at both 1 year and the end of the follow-up, indicating that EUS-RFA can be a successful treatment option.
  • The treatment response in PCNs was notable, with about 70.5% showing significant improvement at 1 year and 66.6% achieving a substantial response by the end of the study
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