Introduction: Juvenile idiopathic arthritis (JIA) poses lifelong challenges due to chronic inflammation that can lead to permanent deformities like autofusion, severely affecting quality of life.
Case Report: In this case, a 31-year-old female with a 21-year history of bilateral knee pain secondary to JIA faced a unique challenge: bilateral knee autofusion. Radiographs revealed severe bilateral contractures, erosive changes, and autofusion, prompting the decision for simultaneous total knee arthroplasties (TKAs).
Objective Platelet-rich plasma (PRP) and adipose-derived stem cells (ADSC) injections are non-surgical treatments for knee osteoarthritis (OA). The purpose of this study is to assess the effectiveness of serial PRP with or without ADSC injections in the treatment of refractory OA of the knee. Design Patients who failed to achieve pain relief with conventional non-surgical treatments, with Kellgren-Lawrence grade 3 or 4 knee OA, were recruited from a private outpatient clinic.
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