Stability of the gut microbiota in persons with paediatric-onset multiple sclerosis and related demyelinating diseases.

Objective: Examine if the gut microbiota composition changes across repeated samples in paediatric-onset multiple sclerosis (MS) or monophasic-acquired demyelinating syndromes (monoADS).

Methods: A total of 36 individuals (18 MS/18 monoADS) with ⩾2 stool samples were included. Stool sample-derived DNA was sequenced.

Safety of dimethyl fumarate for multiple sclerosis: A systematic review and meta-analysis.

Background: The safety profile of dimethyl fumarate (DMF) for multiple sclerosis (MS) is not fully understood.

Objective: To systematically review the literature for adverse events (AE) associated with DMF for MS.

Methods: We searched MEDLINE, EMBASE, CINAHL, Web of Science, CENTRAL, and clinicaltrials.