Publications by authors named "Geoffrey Katana"
Background: Seroprevalence studies are an alternative approach to estimating the extent of transmission of SARS-CoV-2 and the evolution of the pandemic in different geographical settings. We aimed to determine the SARS-CoV-2 seroprevalence from March 2020 to March 2022 in a rural and urban setting in Kilifi County, Kenya.
Methods: We obtained representative random samples of stored serum from a pregnancy cohort study for the period March 2020 to March 2022 and tested for antibodies against the spike protein using a qualitative SARS-CoV-2 ELISA kit (Wantai, total antibodies).
Article Synopsis
- The study examines TB/HIV co-infection trends and treatment outcomes in Kenya from 2012 to 2020, focusing on a large population of TB patients.
- A significant decline in the proportion of HIV-infected TB patients from 32% in 2012 to 24% in 2020 was observed, along with high treatment adherence rates for TB and anti-retroviral therapy.
- However, HIV-infected individuals faced lower odds of completing TB treatment and had a higher risk of mortality and defaulting on treatment compared to those who were HIV-negative.
Background: Tuberculosis (TB) is one of the leading causes of deaths in Africa, monitoring its treatment outcome is essential to evaluate treatment effectiveness. The study aimed to evaluate proportion of poor TB treatment outcomes (PTO) and its determinants during six-months of treatment at Kilifi County, Kenya.
Methods: We conducted a retrospective analysis of data from the TB surveillance system (TIBU) in Kilifi County, Kenya from 2012 to 2019.
HIV stigma in Kenya: A family medicine led community orientated primary care approach.
Afr J Prim Health Care Fam Med
October 2021
The Kenyan Ministry of Health envisages that family physicians should play an important role in the implementation of community orientated primary care (COPC) in collaboration with the community health team. The Kenyan Community Health Strategy forms a solid basis for the implementation of the COPC model. Residents and faculty of the Family Medicine department at the Aga Khan University Hospital Nairobi collaborated with the Kaloleni sub-county of Kilifi County government near Mombasa in a five-step COPC process to better understand and act against the high prevalence of HIV stigma in the coastal region.
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- In 2016, TB caused 1.7 million deaths globally, prompting a study in Kilifi County, Kenya, to analyze all-cause mortality rates and associated features among TB patients from 2012 to 2016.
- The analysis involved 10,717 patients, revealing a 5.5% mortality rate, which increased from 7.8 to 17.7 deaths per 100 person-years over the study period, with most deaths occurring within the first three months post-treatment initiation.
- Significant risk factors for mortality included age, gender, type of TB, malnutrition, HIV status, and the year of diagnosis, highlighting the need for further research into the underlying causes of increasing mortality rates among TB patients.