Publications by authors named "Geoff Sedor"
Radiation therapy (RT) has not been prominent in the treatment of penile cancer because of poorly reproducible results when used in the adjuvant setting. A genomic signature has recently been described that assays radiosensitivity of tumors and informs radiotherapy doses in these cases. Clinical validation in more than 1600 patients demonstrated associations with both overall survival and time to first recurrence.
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- - Personal protective equipment (PPE) is essential for the safety of both medical staff and patients, especially during pandemics like COVID-19, leading to a significant demand-supply gap.
- - The study explores a method for decontaminating PPE, specifically N95 respirator masks, using ultraviolet (UV) radiation in biosafety cabinets, which are found in many healthcare settings.
- - Results indicate that effective decontamination requires UV-C exposure for a minimum of 15 minutes, successfully inactivating the human coronavirus NL63, thus supporting healthcare organizations in preserving PPE supplies.
Introduction: Cancer sequencing efforts have revealed that cancer is the most complex and heterogeneous disease that affects humans. However, radiation therapy (RT), one of the most common cancer treatments, is prescribed on the basis of an empirical one-size-fits-all approach. We propose that the field of radiation oncology is operating under an outdated null hypothesis: that all patients are biologically similar and should uniformly respond to the same dose of radiation.
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