Publications by authors named "Genyang Jin"
Background: Surgical site infection is one of the serious complications of transforaminal lumbar interbody fusion surgery, and many factors affect its occurrence.
Methods: A total of 1,277 patients who underwent transforaminal lumbar interbody fusion between 2018 and 2021 were enrolled in this study. Subsequently, 1,277 patients were randomly assigned to a training cohort (N = 958) and a validation cohort (N = 319) in a 3:1 ratio.
Background: Percutaneous kyphoplasty (PKP) has been demonstrated to be effective in the treatment of osteoporotic vertebral compression fractures (OVCF). However, bilateral puncture techniques take more time to accept more X-ray radiation; some spinal surgeons apply unilateral puncture PKP, but the cement cannot be symmetrically distributed in the vertebral body, so we apply a directional bone cement delivery device that undergoes PKP through the unilateral pedicle puncture. This research aims to compare the clinical and radiological results of PKP via unilateral pedicle approach using a traditional bone cement delivery device and a directional bone cement delivery device and determine the value of a directional delivery device for the therapy of thoracolumbar compression fracture in the elderly.
View Article and Find Full Text PDFObjective: To evaluate the stability and function of the C1-C2 joint after ectopic functional reconstruction (EFR) of the C1 transverse ligament.
Methods: Eight human cadaveric cervical spines (C0-C4) were subjected to in vitro biomechanical test with moment control. Spine specimens were tested under the following conditions: 1) left intact; 2) destabilized by severing the transverse ligament of atlas; 3) after EFR of the transverse ligament.
Article Synopsis
- The study developed a clinical prediction model for osteosarcoma, aiming to enhance predictive ability and reliability, which lacked in previous models made from single-center data.
- Factors such as age, grade, laterality, and metastasis were identified as key predictors, validated by analyzing data from both the SEER database and multiple Chinese medical centers.
- The final model, visualized through tools like a nomogram and a web calculator, demonstrated strong predictive power and is useful for clinical applications in both North American and Chinese patients.
Article Synopsis
- The study investigates genistein's effects on spinal cord injury in mice, focusing on its potential neuroprotective mechanisms.
- Genistein treatment improved exercise recovery, reduced spinal cord swelling, and decreased cell death while altering macrophage ratios and inflammation markers in the injured area.
- The findings suggest that genistein may protect nerves by reducing inflammation through the activation of M2 macrophages and inhibiting specific signaling pathways related to inflammation.
Licochalcone B (LicB) is a flavonoid derived from the Chinese medicinal herb Glycyrrhiza uralensis Fisch. Several previous studies have demonstrated the wide range of pharmacological activities shown by LicB. In this study, we investigated the anticancer effects of LicB in osteosarcoma (OS) tumor cells and its underlying mechanisms.
View Article and Find Full Text PDFObjective: We prospectively compared posterior lumbar interbody fusion (PLIF) and transforaminal lumbar interbody fusion (TLIF) used in adult isthmic spondylolisthesis (IS) after surgical reduction with pedicle screws.
Methods: Between January 2009 and December 2010, 66 adult patients with single-level IS were randomly assigned to two groups treated using the PLIF technique (PLIF group, n = 34) and the TLIF technique (TLIF group, n = 32). Both groups were followed up for an average of 30.
Objective: To investigate the recovery of sexual function of surgically treated male patients with cervical spondylotic myelopathy.
Methods: A prospective and a mean 16-month postoperative follow-up were conducted for 22 male patients surgically treated for cervical spondylotic myelopathy complicated by sexual dysfunction. Their neurologic scores were obtained by the Japanese Orthopedic Association (JOA) Scoring System, their sexual function assessed by the International Index of Erectile Function (IIEF), and their pre- and post-operative reflexogenic and psychogenic erection analyzed by comparison.