Insights into the mechanism of a substituted metal center regulating the enzymatic activity of Prussian blue analogues for catalytic antioxidation.

Atom engineering has been demonstrated to be an efficient strategy for optimizing the activities of Prussian blue analogue (PBA)-based nanozymes. Herein, using a series of metal atom-coordinated N PBAs as models, a mechanistic insight into the effect of substituted metal centers on the antioxidant activities of PBA-based nanozymes is provided for the first time. The PBAs exhibit substituted metal atom-dependent antioxidant activities and the optimal Cu-substituted PBAs can effectively protect cells from oxidative stress.

[Correlation analysis of one-year postoperative mortality,preoperative serum indexes and postoperative nutrition guidance in elderly hip fracture patients].

Objective: To analyze the influence of preoperative serum nutritional indexes and postoperative nutritional guidance on 1-year mortality in elderly patients with hip fracture.

Methods: From January 2015 to December 2017, 396 elderly patients with hip fracture were included in the study, including 267 females and 129 males, aged 68 to 80(75.48±2.