Network topology changes in chronic mild traumatic brain injury (mTBI).

Background: In mild traumatic brain injury (mTBI), diffuse axonal injury results in disruption of functional networks in the brain and is thought to be a major contributor to cognitive dysfunction even years after trauma.

Objective: Few studies have assessed longitudinal changes in network topology in chronic mTBI. We utilized a graph theoretical approach to investigate alterations in global network topology based on resting-state functional connectivity in veterans with chronic mTBI.

8-Hydroxyquinoline 1,2,3-triazole derivatives with promising and selective antifungal activity.

Fungal infections that affect humans and plants have increased significantly in recent decades. However, these pathogens are still neglected when compared to other infectious agents. Due to the high prevalence of these infections, the need for new molecules with antifungal potential is recognized, as pathogenic species are developing resistance to the main drugs available.

Grading scale of radiographic findings in the pubic bone and symphysis in athletes.

Purpose: Radiographic abnormalities in the pubic bone and symphysis are often seen in athletes with groin pain. The aim was to create a grading scale of such radiologic changes.

Material And Methods: Plain radiography of the pelvic ring including the pubic bone and the symphysis was performed in 20 male athletes, age 19-35, with long-standing uni- or bilateral groin pain.

Perceived learning needs of the patient undergoing coronary angioplasty: an integrative review of the literature.

Objective: This study presents, through an integrative review, a comprehensive account of the perceived concerns and learning needs of patients in the early recovery period after a coronary angioplasty.

Scope: Nineteen studies involving the patient who has undergone coronary angioplasty were identified using CINAHL and MEDLINE. These studies were examined to compare samples, methods, findings, implications, and suggestions for future research.

Imaging in chronic achilles tendinopathy: a comparison of ultrasonography, magnetic resonance imaging and surgical findings in 27 histologically verified cases.

Objective: To compare information gained by ultrasonography and magnetic resonance imaging (MRI) in chronic achilles tendinopathy with regard to the nature and severity of the lesion.

Design: Imaging of both achilles tendons with ultrasonography and MRI was performed prior to unilateral surgery. Operative findings and histological biopsies together served as a reference.

Radiographic wear assessment in a total knee prosthesis. 5- to 9-year follow-up study of 158 knees.

One hundred fifty-eight Porous-Coated Anatomic (Howmedica, Rutherford, NJ) primary total knee prostheses were evaluated clinically and radiographically to measure the remaining thickness of the plastic insert. Anteroposterior radiographs were taken with the beam guided parallel to the tibial plate by a fluoroscope. The knees were forced into varus and valgus, and the heights of the medial and lateral joint spaces, respectively, were measured with a digitizing table.

Dislocations of the elbow and intraarticular fractures.

Of 23 patients with an elbow dislocation associated with at least one displaced fracture of the radial head, 19 patients had the radial head extirpated two days range, 0-16 days) after injury. In four elbows, redislocation occurred. All four redislocations were associated with a displaced fracture of the coronoid process.

Unstable intertrochanteric fractures of the hip. Treatment with Ender pins compared with a compression hip-screw.

In a prospective, consecutive, randomized study of the treatment of unstable intertrochanteric fractures of the hip, the use of Ender pins was compared with the use of the compression hip-screw. There were more than 100 patients in each treatment group. The patients who were alive six months postoperatively were evaluated.

Skeletal involvement in pustulosis palmo-plantaris with special reference to the sterno-costo-clavicular joints.

Skeletal scintigraphy was performed in patients with pustulosis palmo-plantaris. There was an increased isotope uptake in the sterno-costo-clavicular area in 16 of 73 patients (22%). The skeletal involvement was further studied by computer tomography showing seven characteristics (including unilaterality) typical of the disease.

Surgical versus non-surgical treatment of ligamentous injuries following dislocation of the elbow joint. A prospective randomized study.

Thirty consecutive patients who had dislocation of the elbow without concomitant fracture and who were sixteen years old or more were examined under general anesthesia for stability of the joint at an average of four days after the injury. All of the elbows showed medial and sixteen showed both medial and lateral instability. The patients were then randomly assigned to undergo either non-surgical or surgical treatment of the ligamentous injuries.

Surgical versus nonsurgical treatment of ligamentous injuries following dislocations of the elbow joint.

Sixty-two patients older than 16 years of age at the time of injury were reexamined an average of five years (range, 1 to 12 years) after a dislocation of the elbow without concomitant fracture. Thirty-four were treated nonsurgically with closed reduction and immobilization in a plaster cast. Twenty-eight were treated surgically with primary ligament repair followed by immobilization in plaster.

Socket loosening after hip arthroplasty. Radiographic observations in 241 cases up to 15 years.

Serial radiographs of 241 consecutive, noninfected low friction arthroplasties performed between 1968 and 1972 were evaluated with respect to socket migration and the presence of radiolucencies, progressive or not. The number of intact sockets in 207 cases of arthrosis decreased slowly and, depending on their classification, approached 95-88 per cent about 10 years postoperatively. Contrary to previous reports, we could not observe any increase in the rate of loosening with time; half of the hips were observed for more than 10 years, and only a few cases of socket loosening were found beyond this point.

Radiographic loosening after revision with gentamicin-containing cement for deep infection in total hip arthroplasties.

Seventy-two infected total hip arthroplasties were revised with cement containing gentamicin and were followed up with regular radiograms for periods of up to six years. The infection healed in 61 cases and persisted in 11. An analysis of the radiographic changes in regard to the signs of loosening showed that about half of the cases with a healed infection had a minimal demarcation between bone and cement.

Unicompartmental knee replacement in osteoarthritis: an 8-year follow-up.

Between 1972 and 1974, 34 patients with medial osteoarthritis in the knee were operated on with unicompartmental femorotibial replacement. Four patients were reoperated on, three of whom had had a McIntosh inlay prior to the operation. Seven patients had died and two were lost at the follow-up which took place on average 8 years (7-10 years) after the operation.

Long-term sequelae of simple dislocation of the elbow.

Fifty-two patients with a radiographically verified dislocation of the elbow were re-examined at an average of twenty-four years after injury. Half of the patients had no residual symptoms or signs whatsoever and more than one-third had a slight or moderate decrease in the range of extension, which was associated with slight degenerative change in the joint or with periarticular calcification. No reduction in joint space was evident.

Radiographic versus clinical loosening of the acetabular component in noninfected total hip arthroplasty.

In a series of 100 total hip arthroplasties revised due to various noninfectious causes, intraoperative determinations of the stability of the socket were compared with conventional preoperative radiographs. All seven hips without radiolucency around the cemented socket were found to be stable. Loosening was demonstrated in 6%-31% of the hips with radiolucency, depending on the classification system.

Arthrography of the dislocated elbow joint.

Arthrography has been suggested as a useful tool for diagnosing ligament ruptures. In 14 consecutive patients with non-fractured elbow dislocations arthrography was performed after reduction of the dislocation. One or two days following arthrography all elbows were examined under general anesthesia with regard to stability and half of them were randomized for surgery with exploration and suture of both the ulnar and the radial collateral ligaments.

Thirty-two noninfected total hip arthroplasties revised due to stem loosening.

Thirty-two total hip arthroplasties with radiographic signs of loosening were revised due to pain. Infected hips were excluded from the study on the basis of clinical, radiographic, and laboratory findings. In spite of increased operating time and blood loss, early complications were rare.

Localized bone resorption in the femur in mechanical failure of cemented total hip arthroplasties.

In 70 total hip arthroplasties exchanged because of mechanical loosening of the stem prosthesis, localized bone resorption or scalloping was found in 33 cases. In 19 of the 33 cases the process started at the level of the tip of the stem, which in 15 cases was found to be in direct contact with cortical bone as observed in the radiographs obtained immediately after the primary surgery. In 37 failures without scalloping this metal-to-bone contact was less common.

Ruptures of the supraspinatus tendon. The significance of distally pointing acromioclavicular osteophytes.

The association between distally pointing osteophytes of the acromioclavicular joint and ruptures of the supraspinatus tendon was investigated by two different methods. In a radiologic study, 47 images of shoulders with arthrographically confirmed supraspinatus tendon ruptures were reviewed and compared with 50 images of shoulders without ruptures. Fifty-one percent of the shoulders with supraspinatus tendon ruptures had osteophytes, as compared with 14% of the normal shoulders.

Recurrent and non-recurrent dislocation following total hip arthroplasty.

The rate of post-operative dislocation after primary total hip arthroplasty in 1739 cases was 3.3 per cent; 0.9 per cent being classified as recurrent dislocations.

Radiologic evaluation of the position of the acetabular component of the total hip prosthesis.

A radiologic method for evaluation of the position of the acetabular part of the total hip prosthesis is described. After analysis of the reproducibility it was used to evaluate the position of the acetabular socket in patients operated upon with different types of prostheses.

Mechanical loosening of the femoral head prosthesis in the Charnley total hip arthroplasty.

In 288 Charnley total hip arthroplasties, without sign of infection, loosening of the femoral component, defined as a radiolucent zone between the proximal lateral edge of the prosthesis and the cement, was recorded in 103 cases, or 36%. The zone usually occurred within a few years after the operation. The progression was most obvious in the first 2 years.

Postoperative dislocation in the Charnley and Brunswik total hip arthroplasty.

An analysis of 351 total hip arthroplasties according to the method and design of Charnley and 194 Brunswik snap-fit deepened socket design failed to show any significant difference in the incidence of dislocation. Neither were the angulation of the acetabular prosthesis in the anteroposterior projection, time after operation, experience of the surgeon and displacement of the greater trochanter significantly related to dislocation. The variables of significance were anatomical superior-inferior position of the acetabular prosthesis and possibly the number of previous operations on the hip joint.