[Successful treatment of myelodysplastic syndrome-associated autoinflammatory lymphedema with azacytidine].

An 84-year-old woman presented pancytopenia. She was diagnosed with myelodysplastic syndromes (MDS) with excess blasts-1, however, she declined treatment with azacitidine (AZA). Ten months later, bilaterally symmetrical, non-pitting edema appeared on the lower legs.

Influence of clinical and genetic factors on warfarin dose requirements among Japanese patients.

Objective: The aim of this study was to investigate the influence of clinical and genetic factors on warfarin dose requirements in the Japanese population.

Methods: We enrolled 125 patients on stable warfarin anticoagulant therapy with an international normalized ratio maintained between 1.5 and 3.