Publications by authors named "Gennaro Melchionda"
A consensus-based approach on the management of patients with both psoriasis and psoriatic arthritis in the dermatological and rheumatological settings in Italy: The ADOI PSO-Amore Project.
Dermatol Reports
September 2022
Article Synopsis
- Psoriasis requires a team approach for effective management, particularly involving dermatologists and rheumatologists for patients with both psoriasis and psoriatic arthritis.* -
- A group of experts has developed recommendations on when it's essential for these specialists to collaborate, either together or sequentially, based on different healthcare settings.* -
- The recommendations include organizing a joint care unit for dermatology and rheumatology, outlining a patient journey that can guide future healthcare strategies for diagnosing and treating psoriasis.*
Inflammatory bowel disease (IBD) is a chronic and disabling disorder. Severity of IBD is prominent among refractory with patients with concomitant immune-mediated disorders. Among those patients, dual biological therapy (DBT) has been suggested as an alternative approach to spare steroids and avoid surgery.
View Article and Find Full Text PDFDisturbances in the epigenetic landscape by aberrant methylation of CpG islands can lead to inactivation of cancer-related genes in solid tumors. We analyzed the promoter methylation status of 6 genes previously reported as cancer-specific methylated (MCAM, SSBP2, NISCH, B4GALT1, KIF1A and RASSF1A) in 38 neural crest-derived tumors by quantitative methylation-specific real-time PCR (QMSP). The results demonstrated that the determination of the methylation status of RASSF1A is able to distinguish between normal and tumor samples in cutaneous melanomas, lung carcinoids and small bowel carcinoids.
View Article and Find Full Text PDFBackground: The value of total body skin examination (TBSE) for skin cancer screening is controversial.
Objective: We sought to determine whether TBSE could be helpful in patients with focused skin symptoms who would not otherwise have undergone TBSE.
Methods: In a prospective, multicenter, cross-sectional study consecutive adult patients were recruited during a period of 18 months.