Representational similarity analysis of self- versus other-processing: Effect of trait aggressiveness.

In this study, using the self/other adjective judgment task, we aimed to explore how people perceive themselves in comparison to various other people, including friends, strangers, and those they dislike. Next, using representational similarity analysis, we sought to elucidate how these perceptual similarities and differences are represented in brain activity and how aggressiveness is related to these representations. Behavioral ratings show that, on average, people tend to consider themselves more like their friends than neutral strangers, and least like people they dislike.

Fast changes in default and control network activity underlying intraindividual response time variability in childhood: Does age and sex matter?

Intraindividual response time variability (RTV) is considered as a general marker of neurological health. In adults, the central executive and salience networks (task-positive networks, TPN) and the default mode network (DMN) are critical for RTV. Given that RTV decreases with growing up, and that boys are likely somewhat behind girls with respect to the network development, we aimed to clarify age and sex effects.

Electrophysiological signatures of resting state networks under new environmental conditions.

It is assumed that cognitive processes are provided by the regulatory interactions of different brain networks. The three most stable resting state networks, among which the default mode network (DMN), the central executive network (CEN) and the salience network (SN) are considered to be the key neurocognitive networks for understanding higher cognitive functions. Peculiarities of changes in the connectivity of resting state networks of an individual entering a new environment and after a year of adaptation in this environment remain poorly studied.

Associations of Hyperactivity and Inattention Scores with Theta and Beta Oscillatory Dynamics of EEG in Stop-Signal Task in Healthy Children 7-10 Years Old.

In the current study, we aimed to investigate the associations between the natural variability in hyperactivity and inattention scores, as well as their combination with EEG oscillatory responses in the Stop-Signal task in a sample of healthy children. During performance, the Stop-Signal task EEGs were recorded in 94 Caucasian children (40 girls) from 7 to 10 years. Hyperactivity/inattention and inattention scores positively correlated with RT variability.

How Self-Appraisal Is Mediated by the Brain.

Self-appraisal is a process that leads to the formation of self-esteem, which contributes to subjective well-being and mental health. Neuroimaging studies link self-esteem with the activity of the medial prefrontal cortex (MPFC), right temporoparietal junction (rTPJ), posterior cingulate cortex (PCC), anterior insula (AIns), and dorsolateral prefrontal cortex. It is not known, however, how the process of self-appraisal itself is mediated by the brain and how different nodes of the self-appraisal network interact with each other.

Intrinsic Connectivity Networks in the Self- and Other-Referential Processing.

Neuroimaging studies have revealed a multitude of brain regions associated with self- and other-referential processing, but the question how the distinction between self, close other, and distant other is processed in the brain still remains unanswered. The default mode network (DMN) is the primary network associated with the processing of self, whereas task-positive networks (TPN) are indispensable for the processing of external objects. We hypothesize that self- and close-other-processing would engage DMN more than TPN, whereas distant-other-processing would engage TPN to a greater extent.

Default mode network connections supporting intra-individual variability in typically developing primary school children: An EEG study.

Intraindividual variability in response time (RT) provides information about attention abilities beyond accuracy and mean RT. It could be an endophenotype for a wide range of clinical disorders and a general marker of neurological health or maladaptation. The default mode network (DMN) and the central executive and the salience networks (CEN + SN) support response stability in adults.

Oscillatory dynamics of perception of emotional sentences in healthy subjects with different severity of depressive symptoms.

The aim of the study was to investigate the characteristics of the oscillatory dynamics of brain activity during the perception of negative, positive, and neutral sentences in healthy individuals with differing severity of depressive symptoms at the preclinical stage. The study involved 34 healthy people (22 women). The severity of the symptoms of depression was assessed using Beck's Depression Inventory (BDI II).

EEG cross-frequency correlations as a marker of predisposition to affective disorders.

EEG cross-frequency amplitude-amplitude correlation (CF-AAC) has been considered as a potential marker of social anxiety and other affective disturbances. Functional significance of this phenomenon remains unclear, partly because the majority of studies used channel-level analysis, which precluded the spatial localization of observed effects. It is not also clear whether CF-AAC may serve as a marker of specific pathological conditions and specific states, or a more general predisposition to affective disturbances.

Impact of Polymorphisms in the Serotonin Transporter Gene on Oscillatory Dynamics during Inhibition of Planned Movement in Children.

The serotonin transporter plays an important role in serotonergic neuromodulation. It is known that polymorphisms in the serotonin transporter gene are linked to the dysregulation of emotions. In the current study, we aimed to investigate the impact of variation in the gene encoding serotonin transporter polymorphism on oscillatory dynamics during inhibition of planned movement in the stop signal paradigm.

Cross-Frequency Coupling in Developmental Perspective.

It is generally assumed that different electroencephalogram (EEG) frequency bands are somehow related to different computational modes in the brain. Integration of these computational modes is reflected in the phenomenon of cross-frequency coupling (CFC). On slow temporal scales, CFC may reflect trait-like properties, which posits a question of its developmental trends.

Effect of Cultural Priming on Social Behavior and EEG Correlates of Self-Processing.

Humans are social beings and the self is inevitably conceptualized in terms of social environment. The degree to which the self is perceived as fundamentally similar or fundamentally different from other people is modulated by cultural stereotypes, such as collectivism and individualism. These stereotypes are not hardwired in our brains and individuals differ in the degree to which they adopt the attitudes that define their culture.

EEG dynamics of spontaneous stimulus-independent thoughts.

In this study, we aimed to compare the oscillatory dynamics accompanying self-referential and non-self-referential stimulus-independent thoughts. Electroencephalograms were recorded in 30 healthy participants who were asked to press buttons classifying their spontaneous thoughts as self-referential or non-self-referential. EEG data were analyzed using independent component analysis in conjunction with dipole localization.

Effect of 5-HTTLPR on current source density, connectivity, and topological properties of resting state EEG networks.

The S allele of serotonin transporter gene (5-HTTLPR) has been found to increase the risk of depression and other mental health problems, but some evidence suggests that S-allele carriers outperform subjects carrying the long allele in an array of cognitive tasks. Evidence linking this polymorphism with individual variation in electrophysiological properties of resting state brain networks is very limited. This study investigated the effect of 5-HTTLPR polymorphism on EEG current source density, connectivity, and topological properties of resting state networks.

Task-positive and task-negative networks in major depressive disorder: A combined fMRI and EEG study.

Background: The study of intrinsic connectivity networks, i.e., sets of brain regions that show a high degree of interconnectedness even in the absence of a task, showed that major depressive disorder (MDD) patients demonstrate an increased connectivity within the default mode network (DMN), which is active in a resting state and is implicated in self-referential processing, and a decreased connectivity in task-positive networks (TPNs), which increase their activity in attention tasks.

Resting state connectivity mediates the relationship between collectivism and social cognition.

Humans are intrinsically social beings and it is natural that self-processing is associated with social cognition. The degree to which the self is perceived as a part of social environment is modulated by cultural stereotypes, such as collectivism and individualism. Here, we tested the hypothesis that individuals who endorse collectivist values would spontaneously think more about their relationships with other people and this association would be mediated by connectivity between the medial prefrontal cortex (MPFC) and the rest of the brain.

Resting State Networks Mediate the Effect of Genotype by Environment Interaction on Mental Health.

A number of studies have shown that the presence of short (S) allele of the serotonin transporter-linked polymorphic region (5-HTTLPR) is associated with a higher risk for depression following exposure to stressful life events. These findings are in line with neuroimaging studies showing that 5-HTTLPR polymorphism has an effect on the connectivity among key areas involved in emotion regulation. Here using mediated moderation analysis, we show that electrophysiological manifestations of resting state networks in the alpha frequency band mediate the effect of 5-HTTLPR by stress interaction on depression/anxiety symptoms in a nonclinical sample.

Suppression mediates the effect of 5-HTTLPR by stress interaction on depression.

A number of studies have shown that the presence of short (S), as opposed to long (L), allele of the serotonin transporter-linked polymorphic region (5-HTTLPR) is associated with a higher risk for depression following exposure to stressful life events. However, many other studies failed to confirm this association. One reason for this inconsistency might be the fact that the interaction of the 5-HTTLPR polymorphism with stress may relate not to depression per se, but rather to adaptive or maladaptive emotion regulation strategies.

Depression and implicit emotion processing: An EEG study.

Objectives: Depression is one of the most prevalent mental illnesses and is associated with changes in emotion processing. The aim of this study was to determine the influence of depressive symptoms on EEG oscillatory dynamics accompanying implicit processing of angry and happy facial expressions in 46 healthy subjects.

Methods: The Beck Depression Inventory was used to assess the presence of depressive symptoms in normal subjects.

Effortful control and resting state networks: A longitudinal EEG study.

Resting state networks' (RSNs) architecture is well delineated in mature brain, but our understanding of their development remains limited. Particularly, there are few longitudinal studies. Besides, all existing evidence is obtained using functional magnetic resonance imaging (fMRI) and there are no data on electrophysiological correlates of RSN maturation.

Interactive effect of 5-HTTLPR genotype and age on sources of cortical rhythms in healthy women.

This study was aimed to localize the effects of 5-HTTLPR (serotonin-transporter-linked polymorphic region) on the age differences of spontaneous EEG activity in women using neuroimaging analysis sLORETA (Standardized Low Resolution brain Electromagnetic Tomography). DNA samples extracted from cheek swabs and resting-state EEG recorded at 60 standard leads were collected from young (YW, N=86, 18-35years) and older (OW, N=45; 55-80years) healthy women. We have shown that advanced age was associated with increased posterior EEG desynchronization in S'/S'.

Depressive symptoms and autobiographical memory: A pilot electroencephalography (EEG) study.

Introduction: Functional magnetic resonance imaging studies have shown changes in the activity of medial prefrontal, medial temporal, and occipital regions in major depressive disorder patients during recall of autobiographical memories. Electrophysiological underpinning of these changes is not known. It is also not clear whether they are a part of the clinical picture or appear at preclinical stages in individuals predisposed to depression.

Anxiety, depression, and oscillatory dynamics in a social interaction model.

Although anxiety and depression frequently co-occur and share a substantial part of genetic vulnerability and other risk factors, they are distinct disorders and their effect on social functioning and accompanying cognitive and emotional processing could be different. In this study, in a nonclinical sample, we compared effects of trait anxiety and depressive symptoms on oscillatory dynamics accompanying perception of emotional facial expressions in the context of social interactions. Anxiety was associated with a longer reaction time, with preference of avoidance behavior, and with enhanced event-related alpha desynchronization and diminished theta synchronization.

Task-positive and task-negative networks and their relation to depression: EEG beamformer analysis.

Major Depressive Disorder (MDD) has been associated with predominance of the default-mode network (DMN) over the task-positive network (TPN), which is considered a neurobiological base for ruminative responding. It is not known whether this predominance is a signature of the full-blown MDD or it already exists at preclinical stages. Besides, all relevant evidence has been obtained using fMRI, which allows for a precise spatial characterization of resting state networks (RSNs), but their neural correlates remain elusive.