Objective: The aim: To determine the efficacy of the original hormone-vitamin complex in terms of biochemical activity enhancement and muscle system functional activity restoration in the irradiated rat's descendents.
Patients And Methods: Materials and methods: The activity of NADP-dependent malatedehydrogenase and the content of ATP, ADP and AMP were determined in the blood, myocardium and thigh muscles of rats exposed to ionizing gamma-radiation. The rats were also checked in the forced swimming test.
Objective: The aim: To determine the hormone-vitamin complex impact on the terminal links of glycolysis, the tricarboxylic acids cycle, and the initial stage of glucone¬ogenesis in the muscle tissue in descendants of irradiated animals.
Patients And Methods: Materials and methods: Pyruvate kinase, lactate dehydrogenase, malate dehydrogenase, NADP-dependent malate dehydrogenasee and phosphoenolpyruvate carboxykinase activities, the content of lactate, pyruvate, malate and oxaloacetate were determined in the blood, myocardium and thigh muscles of 66 rats after exposure to ionizing gamma-radiation. Rats were injected by a hormone-vitamin complex which efficacy was determined using the abovementioned indexes.