SHOX gene variants: growth hormone/insulin-like growth factor-1 status and response to growth hormone treatment.

Context: Short stature homeobox-containing gene (SHOX) variants of unknown clinical significance occur frequently among children with short stature, yet their growth hormone (GH)/insulin-like growth factor-1 (IGF-1) status and response to GH have not been studied.

Objective: To define GH and IGF-1 status in children with SHOX variants and assess their response to GH.

Patients And Methods: This is a retrospective review of children with short stature.

National study of continuity clinic satisfaction in pediatric fellowship training.

Background: A national online survey was conducted to evaluate pediatric subspecialty fellow satisfaction regarding continuity clinic experience.

Methods: An anonymous online survey (SurveyMonkey™) was developed to evaluate demographics of the program, clinic organization, and patient and preceptor characteristics, and to compare fellow satisfaction when fellows were the primary providers with faculty supervision versus attending-run clinics assisted by fellows or a combination of the two models. Pediatric subspecialty fellows in a 3-year Accreditation Council for Graduate Medical Education accredited program in the United States (excluding emergency medicine, neonatology, and critical care) were invited to participate.

Foster care and type 1 diabetes in the Bronx: a case series.

Objective: The objective of this retrospective study was to describe the health status of children with type 1 diabetes mellitus (T1DM) in foster care.

Research Design And Methods: A retrospective chart review of children with T1DM in foster care at the Children's Hospital at Montefiore (CHAM) in Bronx, NY, USA, was performed.

Results: All patients were either African American or Hispanic and raised by single mothers.

Characteristics of diabetes after pediatric liver transplant.

Studies of DALT in pediatric recipients describe incidence and risk factors, but diagnostic criteria varied. This study reports characteristics and course of pediatric DALT by established diabetes criteria. Retrospective chart review of pediatric LT recipients evaluated for hyperglycemia (1/1/1997-12/30/2009) and matched, non-diabetic controls.

Hyperglycemia and outcome in the pediatric intensive care unit.

Objective: To identify the frequency of hyperglycemia in children who are nondiabetic and critically ill and assess the independent effect of hyperglycemia on outcome.

Study Design: Consecutive admissions to the pediatric intensive care unit (PICU) were reviewed. The Pediatric Risk of Mortality III score (PRISM) measured patient acuity.

Hyperglycemia in the pediatric intensive care unit.

Purpose Of Review: Studies on critically ill adults demonstrate the benefits of glycemic control. There is a paucity of data, however, in pediatric intensive care settings. This review summarizes sentinel papers in the adult literature, outlines mechanisms by which hyperglycemia mediates its effects in the critically ill, highlighting those described in pediatrics, and discusses studies that associate hyperglycemia with negative outcome in critically ill children.