[Two Cases of Parkinson's Disease Accompanied with Nasogastric Tube Syndrome].

We report 2 cases of patients with Parkinson's disease who exhibited bilateral vocal cord paralysis induced by an indwelling nasogastric tube (N-G tube). Both patients showed abrupt inspiratory stridor after N-G tube placement. A fiberoptic laryngeal examination revealed bilateral vocal cord abductor paralysis (VCAP).

Involvement of mitoKATP channel in protective mechanisms of cerebral ischemic tolerance.

Little work has been performed to determine roles of mitochondrial ATP-sensitive potassium channels (mitoK(ATP)) in ischemic preconditioning (IPC) in brain. To investigate the role on cerebral IPC, we examined effect of 5-hydroxydecanoate (5-HD), a selective mitoK(ATP) blocker, and diazoxide (DZX), a selective mitoK(ATP) opener on various IPC models. An IPC model with gerbil: 2 min bilateral common carotid arteries occlusion (BLCO)+24 h recovery+5 min BLCO.

Urinary 8-hydroxy-2'-deoxyguanosine and serum S100beta in acute cardioembolic stroke patients.

Objective: Our aim was to explore whether free radical damage against DNA exists or not, in human stroke patients.

Method: Urinary 8-hyroxy-2'-deoxyguanosine (8-OHdG) and serum S100beta were measured in acute cardioembolic stroke patients with relatively severe symptoms. During days 3--5 after the onset of stroke, urine was collected for 24 hours for 8-OHdG measurement and serum was sampled for S100beta analysis every day.