Publications by authors named "Genie Min Ju Wu"
Front Cell Dev Biol
June 2023
Article Synopsis
- The ovary's functionality is crucial for female reproduction and is determined by the health of its ovarian follicles, which are formed during fetal and neonatal stages in humans and mice.
- Recent advancements have shown that pluripotent stem cells can differentiate into primordial germ cell-like cells (PGCLCs), which could potentially form ovarian follicles or organoids when cultured with ovarian somatic cells.
- Despite progress in creating ovarian follicles from these stem cells, efficiency is low due to limited understanding of the interactions between PGCLCs and pre-granulosa cells, highlighting the need for further research into the signaling pathways involved in folliculogenesis.
