Mandibular resection and defect reconstruction guided by a contour registration-based augmented reality system: A preclinical trial.

The aim of this study was to verify the feasibility and accuracy of a contour registration-based augmented reality (AR) system in jaw surgery. An AR system was developed to display the interaction between virtual planning and images of the surgical site in real time. Several trials were performed with the guidance of the AR system and the surgical guide.

Concentrated Growth Factors Promote hBMSCs Osteogenic Differentiation in a Co-Culture System With HUVECs.

Osteogenesis is a complex physiologic process that occurs during bone regeneration. This process requires several growth factors that act on bone marrow-derived mesenchymal stem cells (BMSCs). Concentrated growth factor (CGF) is a new-generation platelet-rich derivative that is an appealing autologous material for application in tissue repair and bone regenerative medicine because it contains a variety of fibrin and growth factors.

Accurate preoperative staging with [Ga]Ga-FAPI PET/CT for patients with oral squamous cell carcinoma: a comparison to 2-[F]FDG PET/CT.

Objective: To evaluate the potential value of [Ga]Ga-labelled fibroblast activation protein inhibitor ([Ga]Ga-FAPI) positron emission tomography/computed tomography (PET/CT) in preoperative staging for patients with oral squamous cell carcinoma (OSCC) as compared to 2-[F]fluoro-2-deoxy-D-glucose (2-[F]FDG) PET/CT.

Methods: Thirty-six treatment-naïve patients with OSCC who underwent 2-[F]FDG and [Ga]Ga-FAPI PET/CT for preoperative staging were enrolled. The maximum standardised uptake value (SUV) of the primary tumour and suspected cervical metastatic lymph nodes, and the tumour-to-background ratio (TBR) of the primary tumour, were measured.