Optimized microwave absorption and thermal properties for TiB@BN/PDMS composites via TiB@BN heterogeneous interface engineering.

The single electromagnetic (EM) wave loss mechanism leads to suboptimal microwave absorption in dielectric materials, whereas, introducing different materials and constructing distinctive microstructures can significantly improve microwave absorption. In this study, TiB and TiB@BN powders were synthesized using boron thermal reduction and chemical solution methods. Their microwave absorption and thermal properties were systematically analyzed.

Lactate Ameliorates Kainic Acid-Induced Neuroinflammation and Cognitive Impairment via the Chemokine Signaling Pathway in Mice.

Purpose: Lactate, previously considered a metabolic waste product, has been shown to have neuroprotective potential. This study aims to investigate the impact of lactate intervention and its underlying mechanisms on epilepsy.

Methods: HT22 cells were stimulated with glutamate to construct an excitotoxicity cell model.

Macrophage membrane‒biomimetic nanoparticles target inflammatory microenvironment for epilepsy treatment.

The clinical treatment of epilepsy is faced with challenges. On the one hand, the effectiveness of existing antiepileptic drugs (AEDs) is limited by the blood‒brain barrier (BBB); on the other hand, changes in the inflammatory microenvironment during epileptogenesis are often neglected. The death-associated protein kinase 1 inhibitor TC-DAPK6 and the fluorescent probe rhodamine B were encapsulated in hollow mesoporous silica nanocarriers (HMSNs), which were then coated with a macrophage membrane to prepare macrophage membrane-biomimetic nanoparticles, namely, MA@RT-HMSNs.

A Case of Brucellosis Concomitant with Severe Fever with Thrombocytopenia Syndrome - Weifang City, Shandong Province, China, 2023.

What Is Already Known About This Topic?: Brucellosis and severe fever with thrombocytopenia syndrome (SFTS) are neglected zoonoses, attributable respectively to and the SFTS virus (SFTSV). While the incidence of these diseases has been rising, instances of co-infection remain uncommon.

What Is Added By This Report?: This represents the first documented case of a rare coinfection involving and SFTSV.

Complementary vitrification of municipal solid waste incineration fly ash from grate furnaces and fluidised bed incinerators via a co-reduction process.

The increasing application of municipal solid waste incineration (MSWI) emphasises the need for MSWI fly ash (FA) safe treatment. Based on the compositional complementarity of FA from grate furnaces (G-FA) and fluidised bed incinerators (F-FA), we proposed a co-reduction process to treat G-FA and F-FA together for producing vitrified slag and ferroalloys. The clean vitrified slag and Fe-Cr-Ni-Cu alloy were obtained with the mass ratios of 1:9 ∼ 6:4 (G-FA:F-FA) at 1300℃, which is about 300℃ lower than the conventional G-FA vitrification.

Research and Validation of CF/PEEK-Based Truss Rod Crimping and Pultruding Process for On-Orbit Isoform Forming.

A crimping and pultruding forming process for truss rods using Carbon Fiber (CF)/Polyether-Ether-Ketone (PEEK) prepreg tape as the raw material is proposed to address the problem of continuous manufacturing of space trusses on orbit. The proposed process provides material rods for continuous truss manufacturing. Through numerical simulation and experimental verification, the effects of relevant parameters on the forming process are determined, an efficient method of rod curl pultrusion, in-rail, equal material forming is proposed, and the structural configuration of the rod curl pultrusion forming mold is determined.

but not is the avirulence determinant in melon carrying the resistance against watermelon mosaic virus, although they contain a common genetic determinant.

Viruses employ a series of diverse translational strategies to expand their coding capacity, which produces viral proteins with common domains and entangles virus-host interactions. P3N-PIPO, which is a transcriptional slippage product from the cistron, is a potyviral protein dedicated to intercellular movement. Here, we show that P3N-PIPO from watermelon mosaic virus (WMV) triggers cell death when transiently expressed in accession PI 414723 carrying the resistance gene.

A Membrane-Free Rechargeable Seawater Battery Unlocked by Lattice Engineering.

Seawater batteries that directly utilize natural seawater as electrolytes are ideal sustainable aqueous devices with high safety, exceedingly low cost, and environmental friendliness. However, the present seawater batteries are either primary batteries or rechargeable half-seawater/half-nonaqueous batteries because of the lack of suitable anode working in seawater. Here, a unique lattice engineering to unlock the electrochemically inert anatase TiO anode to be highly active for the reversible uptake of multiple cations (Na, Mg, and Ca) in aqueous electrolytes is demonstrated.

A Facile and Green Approach for the Preparation of Amine-Functionalized Poly(ethylene glycol) by Reducing Poly(ethylene glycol) Azide with Dithiothreitol.

A facile and green approach for the preparation of PEG-NHs from PEG-Ns in water with DTT as the reduction reagent has been developed, avoiding the introduction of metal ions and difficulties in purification compared to the traditional synthesis process of PEG-NHs. A series of high-purity linear and multiarm PEG-NHs with different molecular weights were synthesized, demonstrating the versatility of this method. Additionally, HS-PEG-NH with high fidelity of thiol and amine was easily prepared through the one-step two functional group conversion of N-PEG-S-S-PEG-N, and the PEG-based NH-PEG@AuNPs were also prepared.

A natural substitution of a conserved amino acid in eIF4E confers resistance against multiple potyviruses.

Eukaryotic translation initiation factor 4E (eIF4E), which plays a pivotal role in initiating translation in eukaryotic organisms, is often hijacked by the viral genome-linked protein to facilitate the infection of potyviruses. In this study, we found that the naturally occurring amino acid substitution D71G in eIF4E is widely present in potyvirus-resistant watermelon accessions and disrupts the interaction between watermelon eIF4E and viral genome-linked protein of papaya ringspot virus-watermelon strain, zucchini yellow mosaic virus or watermelon mosaic virus. Multiple sequence alignment and protein modelling showed that the amino acid residue D located in the cap-binding pocket of eIF4E is strictly conserved in many plant species.

Changes in retinal and choroidal thickness and vascular density in patients with systemic lupus erythematosus: Assessed by optical coherence tomography angiography.

Objective: The aim was to investigate the changes in retinal and choroidal thickness and vascular density in patients with systemic lupus erythematosus (SLE) using optical coherence tomography angiography (OCTA).

Methods: Twenty-nine patients with SLE (29 eyes) and 25 control subjects (25 eyes) were enrolled. SLE activity was assessed using the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI).

Pedestrian detection algorithm integrating large kernel attention and YOLOV5 lightweight model.

In the context of intelligent driving, pedestrian detection faces challenges related to low accuracy in target recognition and positioning. To address this issue, a pedestrian detection algorithm is proposed that integrates a large kernel attention mechanism with the YOLOV5 lightweight model. The algorithm aims to enhance long-term attention and dependence during image processing by fusing the large kernel attention module with the C3 module.

Potato virus Y viral protein 6K1 inhibits the interaction between defense proteins during virus infection.

14-3-3 proteins play vital roles in plant defense against various pathogen invasions. To date, how 14-3-3 affects virus infections in plants remains largely unclear. In this study, we found that Nicotiana benthamiana 14-3-3h interacts with TRANSLATIONALLY CONTROLLED TUMOR PROTEIN (TCTP), a susceptibility factor of potato virus Y (PVY).

Mendelian randomization explores the causal relationships between obesity, diabetes, inflammation and nonalcoholic fatty liver disease.

Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases worldwide. Observational studies have revealed various risk factors associated with NAFLD, while the causal relationships between NAFLD and clinical diseases (including obesity, diabetes and inflammation) remain unclear. In this study, based on the genome-wide association study (GWAS) data, a two-sample Mendelian randomization (MR) analysis was conducted to evaluate the causality between NAFLD and 6 clinical indicators, including body mass index (BMI), waist-to-hip ratio (WHR), C-reactive protein (CRP), fasting blood glucose (FG), fasting insulin (FI), and glycosylated hemoglobin (HbA1c).

Targeting the cochlin/SFRP1/CaMKII axis in the ocular posterior pole prevents the progression of nonpathologic myopia.

Myopia is a major public health issue. However, interventional modalities for nonpathologic myopia are limited due to its complicated pathogenesis and the lack of precise targets. Here, we show that in guinea pig form-deprived myopia (FDM) and lens-induced myopia (LIM) models, the early initiation, phenotypic correlation, and stable maintenance of cochlin protein upregulation at the interface between retinal photoreceptors and retinal pigment epithelium (RPE) is identified by a proteomic analysis of ocular posterior pole tissues.

Advanced root mean square propagation with the warm-up algorithm for fiber coupling.

Fiber coupling plays an important role in applications such as free-space optical communication (FSOC) and self-referencing interferometry. However, the coupling efficiency is often affected by turbulence and platform vibrations, which requires dynamic coupling with optimization algorithms. In this paper, to further mitigate the effects of sudden disturbances and to expand the effective range of fiber coupling systems, we propose a new method called the advanced root mean square propagation with warm-up (ARW) algorithm.

Nanostructured TiO Arrays for Energy Storage.

Because of their extensive specific surface area, excellent charge transfer rate, superior chemical stability, low cost, and Earth abundance, nanostructured titanium dioxide (TiO) arrays have been thoroughly explored during the past few decades. The synthesis methods for TiO nanoarrays, which mainly include hydrothermal/solvothermal processes, vapor-based approaches, templated growth, and top-down fabrication techniques, are summarized, and the mechanisms are also discussed. In order to improve their electrochemical performance, several attempts have been conducted to produce TiO nanoarrays with morphologies and sizes that show tremendous promise for energy storage.

Micro-computed tomography evaluation of the effects of orthodontic force on immature maxillary first molars and alveolar bone mineral density of Sprague-Dawley rats.

Objective: To investigate changes in the immature teeth of Sprague-Dawley rats during orthodontic treatment and to explore the changes in the peri-radicular alveolar bone through micro-computed tomography (CT).

Methods: Twenty-five 26-day-old male Sprague-Dawley rats were included. The maxillary left first molar was moved mesially under a continuous force of 30 cN, and the right first molar served as the control.

Intraocular delivery of ZIF-90-RhB-GW2580 nanoparticles prevents the progression of photoreceptor degeneration.

Photoreceptor degeneration is one of the major causes of progressive blindness which lacks of curative treatment. GW2580, a highly selective inhibitor of colony-stimulating factor 1 receptor, has the protective potential on neurons; however, little was known about the application of GW2580 on photoreceptor degeneration. In this study, BV-2 and 661W cells coculture system was constructed to investigate the interaction between microglia and photoreceptors.