Background: Neonatal sepsis is a leading cause of death in low- and middle- income countries (LMIC). Increasing antibiotic resistance in early onset (< 72 h of life) bloodstream infection (EO-BSI) pathogens in LMIC has reduced the effectiveness of the recommended empiric antibiotic regimen (ampicillin plus gentamicin).
Methods: We retrospectively analysed blood culture-confirmed EO-BSI episodes at nine neonatal units from three central and six peripheral hospitals in the Western Cape Province, South Africa between 1 January 2017 and 31 December 2018.
Geographic variation in the reproductive traits of animal-pollinated plants can be shaped by spatially variable selection imposed by differences in the local pollination environment. We investigated this process in (Iridaceae), an enigmatic species from the Western Cape region of South Africa. has evolved a specialized perch facilitating cross-pollination by sunbirds and displays striking geographic variation in perch size and floral traits.
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