Publications by authors named "Genevieve Morissette"
Background: Acute pulmonary hypertension (aPH) in newborns can be life threatening and challenging to manage. In newborns with refractory aPH, there is currently limited therapeutic agents.
Methods: Retrospective single-center cohort study in newborns less than one month old who were treated with vasopressin for a minimum of one hour in the context of refractory aPH in the neonatal and pediatric intensive care units of a tertiary university center between 2016 and 2022.
Background: Large studies evaluating pediatric acute kidney injury (AKI) epidemiology and outcomes are lacking, partially due to underuse of large administrative health care data.
Objective: To assess the diagnostic accuracy of administrative health care data-defined AKI in children admitted to the pediatric intensive care unit (PICU).
Design: Retrospective cohort study utilizing chart and administrative data.
Background: Persistent pulmonary hypertension of the newborn (PPHN) occurs in 10% of neonatal respiratory insufficiency. To selectively reduce pulmonary vascular resistance, several treatments have been tried. Inhaled epoprostenol (iPGI) has been used for 12 years in our institution for the management of refractory PPHN despite the gaps in the literature to support this use.
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- The study aimed to assess the link between acute kidney injury (AKI) in pediatric intensive care units (PICUs) and long-term mortality, and to see if including urine output data changes this association.
- Conducted as a retrospective cohort study with 2041 children post noncardiac surgery, the results showed that AKI patients had significantly higher mortality rates 5 to 7 years post-discharge despite only a few deaths occurring in the year following hospitalization.
- The research concludes that while AKI is linked to increased long-term mortality, it does not confirm causation, suggesting that high-risk AKI patients warrant special follow-up care until more is understood about these connections.
Background And Objectives: Little is known about the long-term burden of AKI in the pediatric intensive care unit. We aim to evaluate if pediatric AKI is associated with higher health service use post-hospital discharge.
Design, Setting, Participants, & Measurements: This is a retrospective cohort study of children (≤18 years old) admitted to two tertiary centers in Montreal, Canada.
Article Synopsis
- Baseline serum creatinine (bSCr) is crucial for diagnosing acute kidney injury (AKI) in children, but measurements are often missing, especially when height is unavailable for estimating bSCr using equations.
- A study of 538 children in the ICU found that both height-based and height-independent methods underestimated bSCr, but had good agreement in defining AKI compared to measured values.
- The findings suggest that both estimation methods are similar and that they can aid in AKI research and clinical care, particularly when height data is not accessible.
Objectives: To evaluate factors associated with renal recovery from acute kidney injury in critically ill children and the extent to which serum creatinine is measured before discharge.
Design: Retrospective cohort study.
Setting: Two PICUs at tertiary centers in Montreal, QC, Canada.
Background: Extracorporeal treatments (ECTRs) are used for different conditions, including replacement of organ function and poisoning. Current recommendations for ECTRs in various poisonings suggest that intermittent haemodialysis (IHD) is the most efficient technique. However, the practicality of these recommendations is poorly defined in view of limited information on availability and cost worldwide.
View Article and Find Full Text PDFCoronary artery aneurysm is a serious complication of Kawasaki disease (KD). A 3-month-old infant presented with severe KD 27 days after onset of fever. The patient presented with shock, inferolateral ischemia on electrocardiogram and high troponin.
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