Publications by authors named "Genevieve Demeer"

High prevalence of behavioral and psychiatric disorders in adults with Prader-Willi Syndrome (PWS) has been reported in last few years. However, data are confusing and often contradictory. In this article, we propose a model to achieve a better understanding of the psychopathological features in adults with PWS.

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Context: Children with Prader-Willi syndrome (PWS) who receive GH treatment have improved growth and body composition; however, data are lacking for adults when treatment is discontinued after completion of growth.

Objectives: Our aim was to compare body composition and metabolic status in adults with PWS according to GH treatment in childhood and adolescence.

Design: 64 adults (mean age: 25.

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Article Synopsis
  • Prader-Willi syndrome (PWS) is a genetic disorder marked by issues like hypothalamic dysfunction, obesity, and behavioral problems, linked to a reduction in oxytocin-producing neurons.
  • In a controlled study, 24 adults with PWS were given either oxytocin or a placebo to evaluate its effects on social skills and behavior.
  • Results showed that oxytocin administration improved trust, reduced sadness, and decreased disruptive behaviors two days post-treatment, suggesting a potential therapeutic avenue for managing behavioral issues in PWS.
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