Publications by authors named "Genevieve B Marchand"

Unlabelled: Severe obesity is associated with major health issues and bariatric surgery is still the only treatment to offer significant and durable weight loss. Assessment of dietary intakes is an important component of the bariatric surgery process.

Objective: To document the dietary assessment tools that have been used with patients targeted for bariatric surgery and patients who had bariatric surgery and explore the extent to which these tools have been validated.

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The sexual dimorphism in human body fat distribution suggests a causal role for sex hormones. This is of particular importance when considering the role of excess visceral adipose tissue accumulation as a critical determinant of obesity-related cardiometabolic alterations. Scientific literature on the modulation of body fat distribution by androgens in humans is abundant, remarkably inconsistent and difficult to summarize.

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Article Synopsis
  • This study investigates the link between circulating steroid hormone levels and increased body fat in premenopausal women, focusing on how obesity may alter these hormone profiles.
  • The research involved 42 women, measuring 19 plasma steroids and assessing body fat distribution through advanced imaging techniques.
  • Findings revealed negative correlations between certain steroid levels (like androstenedione and pregnenolone) and indicators of adiposity, suggesting that low levels of these hormones may be associated with fat tissue dysfunction and increased inflammation.
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The relationship between circulating estrogen levels and cardiometabolic risk factors such as insulin resistance is unclear in postmenopausal women. High estradiol (E) levels have been reported to predict increased risk of type 2 diabetes in this population. We aimed to examine associations among estrogen levels, adiposity measurements, and cardiometabolic risk variables including insulin resistance in postmenopausal women.

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Background: Biliopancreatic diversion with duodenal switch (BPD-DS) is one of the most effective surgical approaches for the treatment of severe obesity.

Objective: The objective of this study is to compare perioperative complications and long-term results of open BPD-DS in elderly versus younger patients.

Methods: All patients aged 60 years and above who underwent a primary open BPD-DS in our center were selected (n = 105).

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