Background: The chemical composition of plants used in traditional medicine exhibits biologically active compounds, such as tannins, flavonoids, and alkaloids and becomes a promising approach to treat microbial infections, mainly with drug-resistant bacteria.
Objective: The aim of the present study was to evaluate the hydroethanolic leaf extracts of () and () as antimicrobial potential against clinical isolated and Methicillin-resistant .
Materials And Methods: Hydroethanolic leaf extracts were prepared and characterized by high-performance liquid chromatography/diode array detection, Fourier transform infrared, 1,1-diphenyl-2-picrylhydrazyl, and ultraviolet-visible methods.
The reaction of the N-phenyl-2-(1,2,3,4-tetrahydronaphthalen-1-yl-idene)hy-dra-zine-car-bo-thio-amide ligand with zinc acetate dihydrate in a 2:1 molar ratio yielded a yellow solid, which was crystallized from DMSO to obtain the title compound, [Zn(C17H16N3S)2]·C2H6OS. The Zn(II) ion is four-coordinated in a distorted tetra-hedral environment by two deprotonated ligands. Each ligand acts as an N,S-donor, forming a five-membered metallacycle.
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