Publications by authors named "Gene Wolfel"

Article Synopsis
  • Patients with heart failure with reduced ejection fraction (HFrEF) show sustained limitations in their exercise capacity even after receiving a continuous-flow left ventricular assist device (CF-LVAD).
  • The study monitored ten patients' hemodynamics and functional capacity through a series of cardiopulmonary exercise tests before and after CF-LVAD implantation to assess changes with different pump speeds.
  • Results indicated no significant improvement in maximal oxygen uptake or cardiovascular measurements following implantation, suggesting the need for further research on enhancing exercise capacity in HFrEF patients post-device insertion.
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Cytomegalovirus (CMV) is a DNA virus of the Herpesviridae family and is estimated to affect 15%-30% of high-risk solid organ transplant recipients. Typical manifestations of CMV end-organ disease in this population include colitis, esophagitis, and pneumonitis, and myocarditis is a rarely reported manifestation. We describe two cases of CMV myocarditis in solid organ transplant recipients and review the literature regarding previously published cases of CMV myocarditis.

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Background: The prognostic ability of a single measurement of peak oxygen uptake (VO(2)) is well established in patients with chronic heart failure. The relation between a change in peak VO(2) and clinical outcomes is not well defined.

Methods And Results: This investigation determined whether an increase in peak VO(2) was associated with a lower risk of the primary end point of time to all-cause mortality or all-cause hospitalization and 3 secondary end points.

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