Publications by authors named "Gencho D Genchev"
Unlabelled: The AIM of the study was to compare the levels of certain adipose tissue hormones in women with the two main morphological types of obesity - android and gynoid obesity.
Materials And Methods: The study included 2 groups of age- and weight-matched women with android (n = 32) and gynoid (n = 27) type of obesity, and a group of age-matched healthy women (n = 24) with normal weight and body constitution. Leptin, resistin, tumour necrosis factor alpha (TNFalpha), neuropeptide Y (NPY), glucose and insulin were measured.
Effect of short-term standard therapeutic regimens on neuropeptide Y and adipose tissue hormones in overweight insulin-resistant women with polycystic ovary syndrome.
Folia Med (Plovdiv)
March 2012
Article Synopsis
- The study investigated the effects of a 3-month treatment combining oral hormonal contraceptives with either metformin or rosiglitazone on hormone levels and fat-related hormones in women with polycystic ovary syndrome (PCOS).
- A significant reduction in hormones like leptin, resistin, and neuropeptide Y was observed in both treatment groups, along with a notable decrease in body weight specifically for the metformin group.
- Overall, the results indicate that this treatment may lower cardiovascular risks associated with insulin resistance in women suffering from PCOS.
The AIM of the study was to characterize the metabolic syndrome in lean and overweight women with polycystic ovary syndrome (PCOS). The study included 142 premenopausal women distributed into 2 subgroups according to the body mass index: Group 1 with normal weight (n = 39) and Group 2 with overweight (n = 103). The following parameters were measured: basal and oral glucose tolerance test (oGTT)-induced glucose, insulin and triglycerides (TG1), glycated hemoglobin, total, HDL- and LDL-cholesterol; HOMA index and 2 indices of atherogenic risk (total/HDL-cholesterol and atherogenic index) were calculated.
View Article and Find Full Text PDFTo understand the influence of collateral vessels on the coronary flow, TIMI frame count (TFC) method was applied as a measure of mean coronary blood flow velocity in artery giving collateral blood supply to the other artery in angiograms of 76 patients with single occluded coronary artery: RCA giving collaterals to occluded LAD or LAD giving collaterals to occluded RCA. As a control group, TFC was applied in angiograms of 30 patients with mild or no coronary artery disease. TFC was lower (faster blood flow) in LAD giving collaterals to occluded RCA (43 patients) than in LAD in control group (21.
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