Publications by authors named "Genc R"

This study aimed to compare the effect of room arrangement on the mood and milk volume of mothers who gave birth by cesarean section and whose babies were not with them. The study included 89 mothers with and without infants living in the same room (Group 1) and 94 mothers without and without infants living in the same room (Group 2) (n = 183). The expression of milk was performed twice (0-6 h after birth and 36-48 h before discharge) using an electric breast pump.

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This research paper investigates the effect of functionalizing the surfaces of citric acid-synthesized carbon dots (CDs) with hyperbranched bis(methylol)propionic acid (bis-MPA) polyester hydroxyl polymers (HBPs) on their performance as electrode materials in a supercapacitor. Two types of HBPs with 16 and 64 peripheral hydroxyl groups were used to functionalize the CDs' oxygen-enriched surface. Here, CDs were used as electrode materials for the first time in symmetric supercapacitors without a composite material, and how surface modification affects the capacitance performance of CDs was investigated.

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Active food packaging has become attractive because of the possibility to provide a longer shelf-life by loading functional agents into the packages to maintain the quality of food products. Herein, photoluminescent and transparent polyvinyl alcohol (PVA)-based composites embedding multicolor fluorescent carbon dots (CD/PVA) were prepared by the solvent casting method. The prepared CDs emit a strong and stable fluorescence in solution while the CD/PVA composite films were transparent, flexible, and showed UV-blocking activity with a strong fluorescence emission.

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This study conducted on 66 mothers aimed to investigate the effect of foot massages postpartum using an introductory information form, the Postpartum Comfort Scale, the visual analog scale, and a drug follow-up card. It was concluded that foot massages positively improved comfort, reduced pain levels, and reduced unnecessary medications.

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Astragaloside VII (AST-VII), a major cycloartane saponin isolated from Turkish Astragalus species, turned out to be one of the most active metabolites demonstrating Th1/Th2 balanced immune response. As Quillaja saponins are extensively used in adjuvant systems, this study made an attempt to improve AST-VII based adjuvant systems by using different immunostimulatory/delivery agents (monophosphoryllipid A (MPL), Astragalus polysaccharide (APS) and squalene) and to induce cellular and humoral immune response against a viral vaccine. For this purpose, Newcastle Disease vaccine (NDV) was chosen as a model vaccine.

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The aim of this in vitro study was to evaluate the effects of incorporating fluorescent carbon nanoparticles (FCNs) on the hardness, tear, and tensile bond strength of an acrylic-based tissue conditioner and a silicone-based soft denture liner. FCNs added to an acrylic-based tissue conditioner (Viscogel, Dentsply; Group V) and a silicone-based soft denture liner (Ufigel P, Voco; Group U) were divided into subgroups according to the concentrations (Group 0: no water, Group 1: with only water, Group 2: 0.5% FCNs, Group 3: 1% FCNs and Group 4: 10% FCNs) (n=10/per group).

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Adjuvants are substances that increase the immune response to a given antigen. In the development of novel vaccine adjuvants/systems, saponins are one of the most attractive molecules due to their altered immunomodulatory activities. In this study, we tried to develop PEG (polyethylene glycol)/cholesterol-based lipid nanoparticles (LNPs) to deliver the Astragaloside VII (AST-VII) and potentiate adjuvant properties of AST-VII for the influenza vaccine.

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While carbon-based materials have spearheaded numerous breakthroughs in biomedicine, they also have procreated many logical concerns on their overall toxicity. Carbon dots (CDs) as a respectively new member have been extensively explored in nucleus directed delivery and bioimaging due to their intrinsic fluorescence properties coupled with their small size and surface properties. Although various in vitro/in vivo studies have shown that CDs are mostly biocompatible, sufficient information is lacking regarding genotoxicity of them and underlying mechanisms.

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In the Published article, the article title shows "Differential Immunomodulatory Effect of Carbon Dots Influenced". It should be "Differential Immunomodulatory Effect of Carbon Dots Influenced by the Type of Surface Passivation Agent".

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Carbon nanodots (CDs) are often synthesized from natural sources including honey, molasses, fruits, and foods, and plant extracts simply through caramelization. They have wide biological applications especially as drug delivery vehicles and bioimaging agent due to their small size and biocompatibility. This article details the synthesis of carbon dots from carob and its derivatives by surface passivation with polyethylene glycol (PEG), polyvinyl alcohol (PVA), and alginate (ALG).

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: The present study evaluates the traumatic perception of the birth phenomenon in women with substance-use disorders (SUD) and to investigate the effects of psychoeducation on this perception. : The study was conducted between January and July 2017, and involved 60 women with SUD who were divided into two groups: intervention ( = 30) and control ( = 30). The study was carried out using the semi-experimental "pre-post test matched group model," and the Traumatic Perception of Birth Psychoeducation Program (TPBPP) was applied.

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In this original research, the synthesis of carbon nanodots (CDs) from two different solvent extracts of Nerium oleander by the thermal method was investigated under various physical conditions such as pH, reaction temperature, ionic strength, and surface passivation agent (polyethylene glycol, PEG) presence in the reaction media. The effects of extract types and physical conditions on CDs formation were characterized by UV-Visible spectrophotometry, fluorescence spectrophotometry, Fourier transform infrared spectroscopy and dynamic light scattering analysis. Fluorescent CDs were obtained from PEG included reaction media.

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Polyaniline (PANI) is considered one of the most preferred electrically conductive polymers (CPs), which is widely studied as an electrode material in designing next-generation energy storage devices due to their chemical stability, fast redox reactions between the polymer and the electrolytes, high electrical conductivity, excellent electrochemical performance, and low cost. However, the inferior stability of PANI limits its application. In this work, the benefit of carbon dots (CDots) as light-weight and spherical carbon-based electrodes and fillers that allow the maintenance of the nanostructure of PANI while easing the ionic transport was studied together with the effect of manganese(ii) (Mn) doping on the overall capacitive properties of PANI.

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Adjuvants are chemical/biological substances that are used in vaccines to increase the immunogenicity of antigens. A few adjuvants have been developed for use in human vaccines because of their limitations including lack of efficacy, unacceptable local or systemic toxicity, the difficulty of manufacturing, poor stability, and high cost. For that reasons, novel adjuvants/adjuvant systems are under search.

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In this manuscript, we aimed to report the synthesis of aluminum (Al) incorporated carbon nanodots (CD) and their activities on the immune cells. A green synthesis method involving the in situ doping of the nanodot was conducted. Synthesized nanodots immunomodulatory and immunostimulatory activities were tested in vitro on the macrophages.

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Autocrine growth hormone (GH) signaling is a promoting factor for breast cancer via triggering abnormal cell growth, proliferation, and metastasis, drug resistance. Curcumin (diferuloylmethane), a polyphenol derived from turmeric (Curcuma longa), has anti-proliferative, anti-carcinogenic, anti-hormonal effect via acting on PI3K/Akt, NF-κB and JAK/STAT signaling. Forced GH expression induced epithelial mesenchymal transition (EMT) through stimulation of miR-182-96-183 cluster expression in breast cancer cells.

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Objective: The aim of this study was to explore the effect of reflexology on infantile colic.

Design: A total of 64 babies with colic were included in this study (n = 31: study group; n = 33: control group). Following a pediatrician's diagnosis, two groups (study and control) were created.

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Multi-colored, water soluble fluorescent carbon nanodots (C-Dots) with quantum yield changing from 4.6 to 18.3% were synthesized in multi-gram using dated cola beverage through a simple thermal synthesis method and implemented as conductive and ion donating supercapacitor component.

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Objective: To determine the prevalence of anemia and related factors among women in Turkey.

Methods: This descriptive study was conducted at the outpatient clinics of the Department of Internal Medicine, Ege University Medical School. Randomly selected women were given questionnaires regarding their socio-demographic and obstetric characteristics.

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As one of the building blocks of the cell membrane, lipids and their interaction with neighboring lipids and other molecules, as well as their ability to form different kinds of structures, have garnered immense interest. By exploiting the effective shape and thermal-phase behavior of lipids, we have prepared lipid superstructures such as twisted ribbons and rectangular and hexagonal shaped lipidic nanostructures using the curvature tuned preparation method. These lipidic superstructures were then used as nanoreactor templates for the inorganic synthesis of diversely shaped and sized gold nanostructures exploring different administration routes of reducing agents, citrate, and tetrachloroauric acid, which as a result formed different organizations of gold nanoparticles aligned and guided by the template structure.

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Human papilloma virus (HPV) is one of the most common sexually transmitted agents and its infection is the most established cause of cervical cancer. Midwives play a key position in the implementation of cervical cancer. This descriptive study aimed to determine the level of knowledge concerning HPV and HPV vaccination among 268 midwifery students.

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The synthesis of highly stable ultrasmall monodisperse populations of palladium nanoparticles in the range of 1-3 nm in size was achieved via polyol reduction within 1,2-dioleoyl-sn-glycero-3-phosphor-rac-(1-glycerol) liposomal nanoreactors exploiting glycerol as both reducing and stabilizing agent. The liposome-based green method was compared with synthesis in solution, and the reducing agent concentration and the lipidic composition of the liposomal nanoreactors were demonstrated to have a strong effect on the final size and homogeneity of the palladium nanoparticles. Glycerol molecules acting as capping agent demonstrated the ability to stabilize the palladium nanoparticles over a long period of time, maintaining their homogeneity in size and shape.

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Aim: This study aims to investigate the possible role of H. pylori as a cause of laryngeal squamous cell carcinoma.

Method: This controlled study was performed with 31 consecutive laryngeal cancer and 28 cancer-free patients who underwent direct laryngoscopy and biopsy of laryngeal lesions.

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Liposomes have been extensively used as effective nanocarriers, providing better solubility, higher stability and slower release of drugs compared to free drug administration. They are also preferred due to their nontoxic nature as well as their biodegradability and cell membrane mimicking abilities. In this study, we examined noncovalent integration of a cell penetrating arginine-rich peptide amphiphile into a liposomal formulation of negatively charged 1,2-dioleoyl-sn-glycero-3-[phospho-rac-(1-glycerol)] (DOPG) phospholipids in the presence of cholesterol due to its amphipathic character.

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An amyloid-like peptide molecule self-assembling into one-dimensional nanofiber structure in ethanol was designed and synthesized with functional groups that can bind to gold ions. The peptide nanofibers were used as templates for nucleation and growth of one-dimensional gold nanostructures in the presence of ascorbic acid as reducing agent. We performed multistep seed-mediated synthesis of gold nanoparticles by changing peptide/gold precursor and peptide/reducing agent ratios.

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