Evaluating the Influence of Clinical Data on Inter-Observer Variability in Optic Disc Analysis for AI-Assisted Glaucoma Screening.

Purpose: This study aims to evaluate the inter-observer variability in assessing the optic disc in fundus photographs and its implications for establishing ground truth in AI research.

Methods: Seventy subjects were screened during a screening campaign. Fundus photographs were classified into normal (NL) or abnormal (GS: glaucoma and glaucoma suspects) by two masked glaucoma specialists.