Invasive bacterial infection in children with fever and petechial rash in the emergency department: a national prospective observational study.

Objective: To determine the incidence and clinical predictors of invasive bacterial infection (IBI) in well-appearing children who present to the emergency department (ED) with fever and petechiae.

Design: A prospective, observational, multicentre study was conducted in 18 hospitals between November 2017 and October 2019.

Patients: A total of 688 patients were recruited.

Risk Factors of Serious Bacterial Infection in Previously Healthy Children Older Than 90 Days Old With Fever and Neutropenia.

Background: The main objective was to determine the clinical or analytical factors that independently predict risk of serious bacterial infection (RSBI) in immunocompetent patients older than 90 days given a diagnosis of fever and for whom neutropenia was an incidental finding. The secondary objective was to describe the prevalence of serious bacterial infections (SBIs).

Methods: This is a 3-year-long, multicenter, prospective analytical and observational study carried out at 6 pediatric emergency departments.