Publications by authors named "Gema Marin"
Article Synopsis
- The study investigates the effectiveness and tolerability of different chemotherapy regimens (FOLFOX, CAPOX, CP, and FP) for treating HER2-negative advanced esophagogastric cancer, using data from the AGAMENON-SEOM Spanish registry between 2008 and 2021.
- Results indicate that FOLFOX significantly improves progression-free survival (PFS) compared to the CP regimen, although treatment durations were similar among all groups.
- Adverse effects varied by regimen, with higher rates of fatigue and neuropathy seen in FOLFOX, while CP showed notable incidences of hand-foot syndrome and thromboembolic events.
Background: Over the past years, information about the crosstalk between the epicardial adipose tissue (EAT) and the cardiovascular system has emerged. Notably, in the context of acute myocardial infarction (AMI), EAT might have a potential role in the pathophysiology of ventricular structural changes and function, and the clinical evolution of patients. This study aims to assess the impact of EAT on morpho-functional changes in the left ventricle (LV) and the outcome of patients after an AMI.
View Article and Find Full Text PDFObjective: To analyze the prognostic value of pulmonary artery obstruction versus right-ventricle (RV) dysfunction radiologic indices in cancer-related pulmonary embolism (PE).
Methods: We enrolled 303 consecutive patients with paraneoplastic PE, evaluated by computed tomography pulmonary angiography (CTPA) between 2013 and 2014. The primary outcome measure was serious complications at 15days.
Article Synopsis
- The study explored factors influencing 30-day mortality in cancer patients with pulmonary embolism, analyzing both suspected (SPE) and unsuspected (UPE) cases.
- The cohort consisted of 1,033 patients, with key predictors of mortality identified, such as VTE history, cancer type, disease progression, and vital signs.
- Mortality rates differed; truly asymptomatic UPE patients had a lower rate (3%) compared to UPE with symptoms (20%) and SPE (21%), indicating disease severity significantly impacts short-term mortality outcomes.