The association of angiogenic factors and chronic kidney disease.

Background: There are limited data on the associations of circulating angiogenic factors with chronic kidney disease (CKD). We investigate the associations of circulating vascular endothelial growth factor (VEGF)-A, angiopoietin-1, angiopoietin-1/VEGF-A ratio, VEGF receptor 1 (VEGFR-1), VEGFR-2, and pentraxin-3 with CKD.

Methods: We recruited 201 patients with CKD and 201 community controls without CKD from the greater New Orleans area.